Study Effects of Nano Chitosan-Paracetemol to Inhibition Spread of Colon Cancer
DOI:
https://doi.org/10.36329/jkcm/2025/v4.i2.15418Keywords:
Colon cancer, Cytotoxicity, Nanochitosan, Paracetamol, HCT-29,Abstract
One of the gastrointestinal system's most frequent malignant maximums is colon cancer. Currently, surgical resection is the main course of treatment. Nevertheless, colon cancer is prone to metastasis and recurrence, making the development of an efficient anti-cancer medication imperative.
The present investigation employed FT-IR and 1HNMR technique’s to characterization of the synthesis and examination of nano Chitosan-Paracetemol composites. The cytotoxic potential of the new medicine (Nano Chitosan-Paracetemol composites) was evaluated, which had excellent results in our study, the number of infected cells decreased to (IC50=71.26 µg/ml). This work aimed to validate the cytotoxicity of nano Chitosan-Paracetemol on the colon cancer cell line HCT-29 as well as the efficacy of its reduction of metastasis of colon cancer.
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Copyright (c) 2024 Ousama W. Abdulnabi, Mohammad N. AL-Baiati, Heba A. Abd-Alsalam Alsalame
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