Study the effect of Cortisol resistance in patients with hypertension

Abstract

 Background & objective: hypertension commonly interact, creating a difficult condition with major cardiovascular effects. Patients who have hypertension  are more likely to experience their risk of cardiovascular disease (CVD) , left main disease involvement, and three-vessel                                                                                                               

 Methodology: sixty Patient with hypertention  and thirty healthy are participated in this study. .Their ages ranged between 45-70 years. Samples were taken in the morning when they were fasting ,and it obtained  from the Open Heart Institute, Al-Sadr Teaching Hospital, Najaf, Iraq .                                                                                       

 Results:  The study showed that patients with high blood pressure suffer from a significant increase in cortisol, low-density lipoprotein, cholesterol, and triglycerides, and a significant decrease in high-density lipoprotein, these markers are considered early indicators of heart disease .                                                                                      

Conclusions: From this study it be can concluded  that patients with hypertention  may have cortisol resistance, although patients continue to take treatment, the levels of, cholesterol, and low-density lipoprotein remain high in patients. On the other hand cortisol has high sensitive to predict heart disease in patients with hypertention .                                                    

Abbreviations: HDL-high density lipoprotein, LDL-low density lipoprote, TG-triglyceryde