Evaluation of Toxicom on Broilers Fed Mycotoxin Contaminated Ration and Vaccinated Against Gumboro

Abstract

The aim of this study was to evaluate the possible protective effect of preparation which synthesized in Vitebsk State Academy of Veterinary Medicine adsorbent (Toxicom) 5g\kg diet against the toxic effects of mixed mycotoxins in growing broiler chickens. Total 75 chicks, one week age, were divided into 5 treated groups,15 birds for each. The first group (G1) fed a contaminated ration with mycotoxin and supplemented with toxicom 5g/kg of diet and vaccinated with gumboro vaccine at 15 and 22 days of age. The second group (G2) was fed a ration contaminated with mycotoxin and vaccinated with gumboro vaccine at 15 and 22 days of age and not supplemented with toxicom. The third group (G3) was fed intact broiler ration and vaccinated with gumboro vaccine at 15 and 22 days of age. The fourth group (G4) was only fed a contaminated ration with mycotoxins. The fifth group (G5) was fed intact broiler ration  as a control group. The diet was naturally contaminated with many mycotoxins and analyzed by ELISA and the level of mycotoxins were as follows : Aflatoxin B1 0.001 mg/kg, Dezoxivalenol 1.24 mg/kg, Zearalenon 0.068 mg/kg, Ochratoxin 0.005 mg/kg, T2 toxin 0.09 mg/kg, Fuminisen B1 0.2 mg/kg. The antibody titers for Infectious Bursal Disease vaccine (IBDv) was conducted by ELISA. It was concluded that this preparation which synthesized in Vitebsk State Academy of Veterinary Medicine is protect chickens body weight and decrease the effect of mycotoxins in comparison with the other groups and recommended for using as adsorbent in Republic of Belarus.