Hematological parameters after oral administrated of Levamisole with its activity on nonspecific immunity and total serum protein in sheep

Abstract

In this study (20) ewes where examined and subdivided into two groups, the 1^st group test group (n=10) where treated with Levamisole at dose 2.5 mg/kg while the 2^nd group was untreated and considered control group (n=10) blood samples were collected into EDTA – containing tubes. Blood samples from all were continued at the day 0,7,14 and 21.

The level of erythrocytes count, PCV, Hb, total leukocyte count, differential leukocytes count (manual standard method), total serum protein, albumin and globulin were measured to evaluate this study.

Appropriate statistical methods were used for data analysis, and (P<0.05).was considered as significant. No significant differences were seen for PCV, RBCs, and Hb. Neutrophil level at day 14 and monocyte level at day 21 were significantly higher than in the control group (P<0.05).

The results show insignificant increase in the total protein and Globulin and insignificant decrease in the albumin.

leavamesole enhance nonspecific immune response due to induce leukocytosis, neutrophilia  and monocytosis .