Role of Two Biocides in The Wounds Healing and Side Effect in Rabbits

Abstract

This study was aimed to show the influence of two bioformulation on wounds healing ,side effect in liver and kidneys in rabbits . The results indicated  that no effect on wound healing were observed in bioformulation  treated group compared with the controls. There were toxic effects on the liver which was shown on  histopathological examination as centrilobularvacuolation, necrosis of hepatocytes  around congested central vein, pyogranulomatous lesion around dilated central vein with marked vacuolation of hepatocytes.On kidneys , histopathological results revealed severe hemorrhage in the cortical area between glomeruli and renal tubules, severe atrophy of glomeruli in the cortical area with some congested blood vessels in the renal parenchyma , severe atrophy of glomeruli in the cortical area with some congested blood vessels in the renal parenchyma  and some degree of dilation of renal tubules.