The effect of different concentration of Ethyl alcohol on the seminiferous tubules of the mature rabbits.Histo-physiological study

Abstract

This study was applied to investigate the effect of different concentration of ethyl alcohol on seminiferous tubules in adult male rabbits . the study was conducted on the eighteen mature male rabbits were divided randomly into three groups ,each group have six animals first and second treated group were injected subcutaneously (S/C) four milliliter ethyl alcohol (15%), eight milliliter ethyl alcohol (25%) respectively for period (six) weeks as one dose every 48 hours, The third group was the control which treated  with distil water at the same doses of treated groups . The result showed :-

1.First group was revealed increase in mean diameter of seminiferous tubules (250.75      ± 7.8) micrometer, and decrease in testosterone level ( 18.85 ± 10.52) microgram/milliter. as compared with the control group(distil water).

2. The first and second treated groups were observed impairment in spermatogenic process due to reduction of the testosterone level.

3. Significant increase (P<0.05) in the mean diameter of seminiferous tubules in the second treated group that reached to ( 280 ± 6.85) micrometer. when compared with control group.

4.Degenerative changes and necrosis were occurs in the spermatogenic cells in the first and second treated groups when compared with control group.