Study the Effect of Protexin® as a Probiotic and levamisole on The Immunity of Broilers

Abstract

This study was conducted to evaluate the effect of Protexin^® and levamisole  as an immune modulator. A total of 125 unsexed (Ross 308)  broiler chicks with an average initial body weight of 43g to all chicks at the age of one day were randomly divided into five equally treated  groups (25 chicks per pen ).Group 1 was considered as control group fed with commercial ration without  any additives, group 2 was fed with commercial  ration  with the addition (daily) of  1g protexin^® /liter of drinking water 1- 10 days, 1g protexin /2 liters of drinking water 10-20 days and 1g protexin^® /4 liters of drinking water 20 day- end of the study, group 3 was fed with commercial  ration  with the addition (each 3 days a week) of  1g protexin^® /liter of drinking water 1- 10 days, 1g protexin^® /2 liters of drinking water 10-20 days and 1g protexin^® /4 liters of drinking water 20- end of the study, group 4 was fed with commercial  ration  with the addition of levamisole 10 µg/kg B.w. daily, group 5 was fed with commercial  ration  with the addition of levamisole 10 µg/kg b.w. 3 days a week. The experiment lasted for five weeks (35 days). Chicks were vaccinated against New castle disease (ND) on age ( 10,20,30) days , by drinking water method, also vaccinated against Infectious Bursal Disease (IBD) on age (14) days by drinking water method. At days 1, 12, 22 and 35 blood samples were collected to estimate the immune response by ELISA test for ND and at 35 day for IBD. The titer of antibody (Ab) increased significantly (P ≤0.05) against NDV and IBD in G2 (Protexin^® daily) as compared with G1(control group) at the age of 22 and 35days.