A study of the inhibitory effect of the Ethanolic extract of Cyperus rotundus , Eugenia caryophyllus and Coriandrum sativum on the in vitro growth of Candida albicans on a Sabouraud Dextrose Agar

Abstract

The present study was designed to evaluate the inhibitory effects of three local plant ethanolic extracts (Cyperus rotundus , Eugenia caryophyllus and Cariandrum sativum ) against the growth of Candida albicans in culture media by  using of agar well diffusion method. For this purpose graduate concentrates for each extract ( 25 , 50 , 100 , 150 , 200 , 400 )mg/ml prepared and tested .The result showed that the  extract of Cyperus rotundus was more effective than Eugenia caryophyllus ,while  Coriandrum sativum has no effect in all concentrates on  Candida albicans.

    The statistical analysis by using ANOVA with LSD at level (p<0.05) showed that the  concentrations 200 , 400 mg/ml for Cyperus rotundus and 200 mg/ml for Eugenia caryophyllus were a significantly preeminence on the effect of other concentrations and from the effect of Nystatin and Clotrimazole .