Synthesis and Characterization of some Heterocyclic Compounds from Indole Derivatives

Authors

  • NoorAL-Huda AbdulabbasBahar Department of chemistry-Faculty of Education for Girls-University of Kufa-Iraq
  • Hasan ThamerGhanim Department of chemistry-Faculty of Education for Girls-University of Kufa-Iraq

Keywords:

indole -2- carboxylic acid, Schiff bases, Oxazepine, 1,3-oxazepane, biological activity

Abstract

This research involves preparation of heterocyclic compounds from indole -2- carboxylic acid. The first step synthesized of ester compound from indole -2- carboxylic acid and prepared hydrazinamide from ester.Then prepared Schiff bases from hydrazinamide derivatives with benzaldehyde derivatives. The last step preparedoxazepine and oxazepane derivatives from Schiff bases with(malice, phthalic and succinic)inhydride .These compounds were characterized by melting point ,FT.IR,1HNMRand13C-NMR.

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Published

2023-01-15

How to Cite

NoorAL-Huda AbdulabbasBahar, & Hasan ThamerGhanim. (2023). Synthesis and Characterization of some Heterocyclic Compounds from Indole Derivatives. Journal of Kufa for Chemical Sciences, 2(5), 38-52. https://journal.uokufa.edu.iq/index.php/jkcs/article/view/11030

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