New bis Schiff base of isatin derivatives: syntheses, characterization, and biological activity
DOI:
https://doi.org/10.36329/jkcm/2023/v3.i1.11329Keywords:
Schiff base, Isatin, Biological activity.Abstract
In the current study, imesatin (A) was condensed with various aromatic aldehydes to create a number of new Schiff bases of isatin [B1-B6]. The imesatin were created by combining isatin and O-phenylenediamine. Utilizing FT- IR and 1H-NMR and 13CNMR techniques, the chemical structures of the produced compounds were verified. Staphylococcus aureus, a gram positive bacteria, and Klebsiella pneumonia, a gram negative bacteria, were used to evaluate the biological study at concentrations of 50 and 100 μg/mL. Derivatives were discovered to have biological activity against these bacterial growths.
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