Synthesis and Characterization of some new heterocyclic derivatives from terphthaldehyde and study of their biological activity

Authors

  • Zainab Hassan Rahim Department of Chemistry, College of Education for Girls, University of Kufa, Iraq
  • Nadia Sadiq Majeed Department of Chemistry, College of Education for Girls, University of Kufa, Iraq

DOI:

https://doi.org/10.36329/jkcm/2023/v3.i1.12260

Keywords:

Terphthaldehyde, Chalcones, thiazine

Abstract

In this study, some new heterocyclic compounds have been synthesized including the preparation of some chalcone from the reaction terphthadehyde with two moles of ketone derivative p-hydroxy acetophenone in a basic medium, After that . The stage includes the preparation of new heterocyclic compounds five-membered ( pyrazole, Isoxazole) and six-membered ( oxazine, thiazine). The prepared compounds were characterized by FT-IR,1H-NMR, and 13C-NMR techniqes, in addition to their melting points and TLC (Thin Layer Chromatography).Finally,the prepared compounds are tested against Gram-positive and Gram-negative bacteria to study their biological activity.

Downloads

Download data is not yet available.

Downloads

Published

2023-12-10

How to Cite

Zainab Hassan Rahim, & Nadia Sadiq Majeed. (2023). Synthesis and Characterization of some new heterocyclic derivatives from terphthaldehyde and study of their biological activity. Journal of Kufa for Chemical Sciences, 3(1), 223–239. https://doi.org/10.36329/jkcm/2023/v3.i1.12260

Issue

Vol. 3 No. 1 (2023): Journal Of Kufa For Chemical Sciences

Section

Peer-reviewed Articles

License

Copyright (c) 2023 Journal of Kufa for Chemical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Open-access Statement
The journal « Journal Of Kufa For Chemical Sciences» provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Full-text access to scientific articles of the journal is presented on the official website in the Archives section.

This is in accordance with the BOAI definition of open access. The licensing policy is compatible with the overwhelming majority of open access and archiving policies.

The journal «Journal Of Kufa For Chemical Sciences» is an open access journal, which means all its content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author as long as they cite the source.The journal is licensed by Creative Commons Attribution International( CC Attribution 4.0) .