Synthesis and Characterization of New benzimidazole-nitrone Derivatives, and Study of Their Effect as Anti-bacterial.
DOI:
https://doi.org/10.36329/jkcm/2023/v2.i10.13347Keywords:
BenzimidazoleAbstract
New benzimidazole derivatives (benzimidazole-nitrone) were synthesized from the condensation of o-phenylene diamine with p-amino benzaldehyde in the presence of (P-TsOH\EtOH). Then the benzimidazole compounds that containing an imine group were oxidized to obtain a nitrone group by used peracetic acid and identified by FT-IR, H1-NMR spectra, and elemental analysis. All compounds applied to the Escherichia coli and Staphylococcus aureus gave a different result. The compounds which have (OH, Br, Cl, OCH3) groups appeared activity as anti-bacterial while compound (2) when R=H don’t have activity for each type of bacteria that used
Downloads
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Meaad A. Fadel, Hanaa K. Mousa, Dawood S. Ali
This work is licensed under a Creative Commons Attribution 4.0 International License.
which allows users to copy, create extracts, abstracts, and new works from the Article, alter and revise the Article, and make commercial use of the Article (including reuse and/or resale of the Article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made and the licensor is not represented as endorsing the use made of the work.
How to Cite
