Design, Preparation some transition metal complexes of Chalcone-Azo with Paracetamol ligand and Evaluation anti-biological activity of some complexes
DOI:
https://doi.org/10.36329/jkcm/2023/v3.i1.13523Keywords:
Chalcone-Azo, Paracetamol compound, Thyroid cancer, antimicrobial activity.Abstract
This search designed new series complexes of (Mn , Fe, Co, Ni, Cu, and Pd)(II) ,which prepared from Chalcone - Azo derived contained Paracetamol . The results illustrate that, the mole ratio (ligand : metal) (2:1) for all complexes and the geometric shapes of complexes were an Octahedral except Pd(II) complex was Square planer. the complexes characterized by ( UV-Visible, FTIR, C.H.N, Electrical molar conductivity and Magnetic susceptibility). This ligand coordinated with metal ions via (N) atom of Azo group and (O) atom of OH group of Paracetamol , the biological examination tested Pd(II)complex as antitumor Thyroid cancer cells(FTC-133) and compered it with healthy cells to evaluate the possibility of using it as therapeutic method. In addition , it tested Cu(II) and Ni(II) complexes as antimicrobial activity towards two types of Gram negative and Gram positive bacteria
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Journal of Kufa for Chemical Sciences
This work is licensed under a Creative Commons Attribution 4.0 International License.
Open-access Statement
The journal « Journal Of Kufa For Chemical Sciences» provides immediate open access to its content on the principle that making research freely available to the public supports a greater global exchange of knowledge. Full-text access to scientific articles of the journal is presented on the official website in the Archives section.
This is in accordance with the BOAI definition of open access. The licensing policy is compatible with the overwhelming majority of open access and archiving policies.
The journal «Journal Of Kufa For Chemical Sciences» is an open access journal, which means all its content is freely available without charge to the user or his/her institution. Users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author as long as they cite the source.The journal is licensed by Creative Commons Attribution International( CC Attribution 4.0) .