Microwave-Assisted Synthesis of Five and Seven-Membered Heterocycles and Study Their Biological Activity
DOI:
https://doi.org/10.36329/jkcm/2023/v2.i10.13553Keywords:
AzomethineAbstract
In this study, we synthesized one azo compound (S19) and then condensat this compound with a carbonyl compound to give a Schiff base (S20) as the key step. The next step Schiff base reacted with some Amino acids and Anhydrides by cycloaddition reaction to give five-membered (S22, S23) and seven-membered (S21, S24) heterocyclic compounds. The chemical Structure for of the synthesized compounds were confirmed by using spectroscopic techniques (IR and NMR). In addition, tested their biological activity against Staphylococcus Aureus and Escherichia Coli displayed good activity.
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Copyright (c) 2023 Samah Hassan Hadi, Faez A. Alrammahi
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