Microwave-Assisted Synthesis of Five and Seven-Membered Heterocycles and Study Their Biological Activity

Samah Hassan Hadi; Faez A. Alrammahi

doi:10.36329/jkcm/2023/v2.i10.13553

Microwave-Assisted Synthesis of Five and Seven-Membered Heterocycles and Study Their Biological Activity

Authors

Samah Hassan Hadi *Department of Chemistry, Faculty of Education for Girls, University of Kufa
Faez A. Alrammahi *Department of Chemistry, Faculty of Education for Girls, University of Kufa

DOI:

https://doi.org/10.36329/jkcm/2023/v2.i10.13553

Keywords:

Azomethine

Abstract

In this study, we synthesized one azo compound (S19) and then condensat this compound with a carbonyl compound to give a Schiff base (S20) as the key step. The next step Schiff base reacted with some Amino acids and Anhydrides by cycloaddition reaction to give five-membered (S22, S23) and seven-membered (S21, S24) heterocyclic compounds. The chemical Structure for of the synthesized compounds were confirmed by using spectroscopic techniques (IR and NMR). In addition, tested their biological activity against Staphylococcus Aureus and Escherichia Coli displayed good activity.

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Published

2023-11-05

How to Cite

Samah Hassan Hadi, & Faez A. Alrammahi. (2023). Microwave-Assisted Synthesis of Five and Seven-Membered Heterocycles and Study Their Biological Activity. Journal of Kufa for Chemical Sciences, 2(10), 109–121. https://doi.org/10.36329/jkcm/2023/v2.i10.13553

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Issue

Vol. 2 No. 10 (2023): Journal Of Kufa For Chemical Sciences

Section

Peer-reviewed Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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