Levels of Chromium as a biomarker for detection of Lung Cancer

Abstract

The current study focused on estimating the level of chromium in biological tissues such as nails using inductively coupled plasma-atomic emission spectroscopy (ICP-AES) technology, as this technique is distinguished by its ability to estimate small amounts of chromium up to 0.005ppm. A number of parameters were used in this study such us Age, gender, as well as a comparison between people who smoke and non-smokers to estimate the level of chromium. 122 samples were collected and divided into two parts, including 55 models for people with lung cancer and 67 models for healthy people. The results showed a high percentage of chromium in people with lung cancer (0.2757 ± 0.0209 ). ) Compared to healthy people (0.0437 ± 0.0044 ). The study found that one of the causes of high levels of chromium in lung cancer patients is due to smoking, as the percentage of chromium in affected smokers reached (0.2665 ± 0.0262 ) compared to non-smokers (0.0875 ± 0.0103 ). A comparison was also made between the percentage of chromium in infected men and women. The study found a higher percentage of chromium in men (0.2230 ± 0.02050 ) in comparison to females (0.0646 ± 0.00987 ) because men are more addicted to smoking than women. In this study, a statistical analysis program was used SPSS at P < 0.05).