Preparation, Diagnosis and Study of the Effect of the Biological Activity of Multi Dentate Azo- Schiff Ligand and Cu(II), Zn(II) Complexes

Abstract

The New azo-Schiff ligand was prepared through two paths. The first path is the reaction of the primary aromatic amine( 4-ethoxyaniline) with benzaldehyde to form the azo compound. The second path included condensation of the resulting compound with the aliphatic amine ethylenediamine and the addition of two drops of glacial acetic acid to prepare the azo-Schiff ligand.  The final analysis was done using infrared spectroscopy, ultraviolet-visible spectroscopy, mass spectrometry, proton nuclear resonance spectroscopy, and elemental analysis (C.H.N.). Solid metal complexes were prepared for the ligand prepared with the metal ions Cu(II), Zn(II), and all the complexes were characterized by the above techniques, except for mass spectrometry and ¹HMNR measurements for the final ligand only. As for the study of the molar conductivity and magnetic susceptibility of the metal complexes prepared and dissolved in ethanol at room temperature and at a concentration of (1×10^-3)M proposed the geometric shape of the prepared complexes, all of which were octahedral, The last path  includes studying the extent to which the biological activity of the azo-Schiff ligand and its complexes affects for two types of bacteria,For both Escherichia coli and staphylococcus aureus , at two concentrations( 250ppm) and (500 ppm).