Hemorrhagic Fever history, Diagnosis and Treatment: review article

Abstract

   Hemorrhagic fever viruses are  risks to public health around the world because they can cause very deadly diseases to emerge and reappear. The viruses causing viral hemorrhagic fevers (VHFs) typically produce acute febrile illness, coagulation problems, and widespread bleeding, which can lead to potentially fatal organ failure. Four virus families are responsible for viral hemorrhagic fever (VHF), one of which is Filoviridae. The Filoviridae family includes the Ebola virus , is responsible for the current VHF outbreak in West Africa. Viral hemorrhagic fevers (VHFs) occur in various regions around the world, yet traditional diagnostic testing for these diseases has typically been conducted in major reference laboratories located in Europe and the United States.In this review, we explore the current understanding of the mechanisms driving the pathogenesis of viral hemorrhagic fevers (VHFs) and examine the progress in developing preventive and therapeutic strategies for these infections.