Determination of Zinc, Copper and Antioxidant Vitamins in Iraqi Patients with Celiac Disease

Abstract

Celiac disease is a complicated and clinical disorder results from incapability of the immunity system to complete the metabolic reaction which is responsible for benefit of gluten protein abundant in plants foods such as wheat, barley and rye. Vitamins A and C were determined by Elisa technique whereas trace elements (copper and zinc) were determined Spectro-photometrically. Therefore, the present research was employed to investigate and measure the concentrations of some vitamins and trace elements in Iraqi celiac patients according to body mass index and family history factors. It was found high significant increases ( ⃰⃰  ⃰  ⃰P<0.0001) of concentrations of antioxidant vitamins A was recorded celiac patients in comparison with healthy persons (control groups), depending on body mass index variable and significant decrease ( ⃰⃰  ⃰ P<0.001) in concentrations of vitamins A and C according to family history variable. The Trace elements (Cu) showed a significant decrease (⃰  ⃰ P<0.001) in Its concentrations values according to body mass index variable especially at obese status. Also, significant decrease in Zn concentration and increases in Cu concentration (⃰ P< 0.05) was noticed the celiac patients which have family history. compared with the patients having no family history. As conculsion, body mass index and family history are important variables for estimation of vitamin A, vitamin C, copper and zinc concentrations in celiac patients.