Knowledge, Attitudes and Practices of Physicians Toward Drugs Induced QT Prolongation

Abstract

Prolonged QTc intervals are a common and clinically significant issue, associated with an increased risk of cardiovascular events and overall mortality. Medication-induced QT prolongation is a frequent cause, involving widely used drugs such as antiarrhythmics, antidepressants, antibiotics, and antipsychotics. Addressing this risk requires improved physician awareness and proactive monitoring. This cross sectional study aimed to enhance the practice of physicians toward drug-induced QT prolongation and related cardiac events. Conducted over three months from January 15 to April 15, 2025, the study took place at Imam Al-Sadiq Teaching Hospital in Al-Hilla. 53 physicians were interviewed regarding their knowledge, attitude, and practice toward QT prolongation. The majority of participating physicians were under 40 years old, predominantly male (67.9%), and most commonly specialized in internal medicine (45.3%). Regarding their years of practice, 37.7% had been practicing medicine for(less)than 5 years, (28.3%)had between 5 and 10 years of (experience, and 34.0% had over (10 years) of experience. In the term of knowledge, 5.7% of physicians have a good knowledge and 94.3% have a bad knowledge. favourable attitude was present in 24.5%. adequate practice was found in 67.9% while 32.1% of physicians had inadequate practice. This study shows a bad knowledge, unfavourable attitudes and adequate practices among physicians about drugs induced QT prolongation.