A Comparative Study Between of Effect of Tramadol and Xylazine as Premedication Those Followed by Ketamine Anesthesia in Dogs

Abstract

The analgesic effects of Tramadol and Xylazine as a preanesthetic in followed by Ketamine in adult dogs. A twelve male was randomly divided in to three groups . first group serves as control group  given normal saline, a second 4mg /kg B.W. i.m. of Tramadol  and third group 1 mg/kg B.W. i.m.  Xylazine premedication, was then administered intramuscular followed by Ketamine anesthesia at dose 5 mg/kg B.w.. The behavioral changes, the duration of surgical anesthesia, and biochemical parameters. Xylazine  pretreatment significantly (P<0.05) increased the degree of sedation when compared with the control. The duration of surgical anesthesia was significantly (P<0.05) increased by Tramadol  pretreatment when compared with control group. There were no significant (P<0.05) differences in biochemical tests total Protein, Creatinine, Alanine Transaminase ALT and Aspartate Transaminase AST among the groups. This result suggests that intrmuscular Tramadol at 4mg /kg is a useful preanesthetic agent for extending the surgical level of anesthesia in ketamine anesthesia in dogs.