Evaluation of Some Biochemical Parameters in Patients With Metabolic Syndrome

Abstract

Background: Metabolic syndrome is the medical term for a cluster of metabolic abnormalities that increases in individuals risk of diabetic mellitus type 2 ( T2DM  ) and cardiovascular diseases(CVD)._ENREF_1 The components of MS are glucose intolerance, obesity, hypertension and dyslipidemia.An insulin resistance is the key phase of metabolic syndrome constitutes the major risk factor for the development of diabetes mellitus.

Objectives:The present study aimed to comprise insulin resistance values among  three study groups.

Subjects: The present study included 50 metabolic syndrome patients, 50 cases who suffered at least one of the metabolic syndrome symptoms as pathological control, finally 50 individuals as healthy control.

Methods: Fasting insulin, hemoglobin A_1C (HbA_1C), fasting  blood glucose and the lipid profile includedtotal cholesterol TC, triglyceride TG and high density lipoprotein cholesterol HDL- and low density lipoprotein cholesterol LDL-C concentrations were determined in present study using a different available kits.

Results:current work showed a highly significant variations among study groups, no significant differences were shown when the comparison was carried out between two  genders of the same subgroups.