Preparations, Reactions and Biological Activities of 1,3,4-Thiadiazole Derivatives: Reviewing Study

Abstract

1,3,4-thiazole ring consider one of most important and common from five membered heterocycle compounds present in many from variety natural products and medical agents. The 1,3,4-thiadiazole ring exhibit variety wide spectrum from pharmacological activities such as anti-inflammatory, antimicrobial, antiepileptic, antineoplastic, analgesic, antiviral, anticancer and as antitubercular etc. The wide and vigorous activities for thiadiazole ring and also their derivatives make them a bioactive important compounds and from this importance the attempt to write this review came to highlighted about their reactions, their synthesis methods and also their pharmacologically applications.