Synthesis , Chalcone and Study of the Biological Activity for Different Heterocyclic Compounds from the Chalcone Derivative.
Keywords:
Chalcone, Thiazine, Oxazine, Pyrazole, diazepineAbstract
This study included preparation and characterization of the chalicon compound that which prepared from reaction terephthalaldehyde with 4-bromoasetopheone and also prepared a number of heterocyclic compounds from the chalicon derivative with (Thiourea), (urea), (2,4-dinitrophenyl hydrazine),( 1,2-diamine-benzene) these dreivatives are (Thiazine, Oxazine, Pyrazole, diazepine). All the prepared compounds were diagnosed by means of the FT-IR spectra and the proton 1H.NMR spectra. Then the bio-activity of these compounds and their effect on two types of bacteria (staphylococcus, Escherichia coli) were studied some compounds were identified that have a strong inhibitory effect.
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