Ethyl Aceto Acetate as starting material for preparation pyrazol ring Derivatives

Abstract

The current study includes organic synthesis of some new pyrazol derivatives from 2-amino thiazole by prepare diazonium salt from it with Ethyl Aceto Acetate as coupling compound to form Azo compound (B). From this azo compound, pyrazol Derivatives are prepared by closing the Aceto and Aster groups via hydrazine and phenyl hydrazine under Microwave irradiation respectively . The other step is the preparation of Chalcone derivative(CH) from Azo compound  (B) with p-N,N-di methyl amino banzaldehyde.  also pyrazol Derivative was  prepared by reaction the Chalcone derivative with hydrazine hydrate in acidic and basic medium  . These compounds are identified and confirmed by FT- IR, ¹HNMR, ¹³CNMR.