Synthesis and biological activity of 2-(4,5-dihydro-1H-pyrazol-1-yl)-1,3-benzothiazole derivatives

Authors

  • Abbas A. Mohammed Mustansiriyah University, College of Science, Department of Chemistry, Baghdad, Iraq
  • Hamid H. Mohammed Mustansiriyah University, College of Science, Department of Chemistry, Baghdad, Iraq
  • Mustafa T. Mustansiriyah University, College of Science, Department of Chemistry, Baghdad, Iraq
  • Zainab N. Mageed Mustansiriyah University, College of Science, unit of research polymer, Baghdad, Iraq

Keywords:

Benzothiazole, Antibacterial activity, Antifungal activity, Pyrazole

Abstract

In this work include synthesis some of 2-(4,5-dihydro-1H-pyrazol-1-yl)-1,3-benzothiazole derivatives were synthesized from 2-hydrazino-1,3-benzothiazole with dicarbonyl compounds, compounds (8 and 9) synthesis with microwave assistance. The biological activity for some compounds (2-5) were studied against (gram +ve) bacteria, (gram –ve) bacteria; and antifungal activity against and the data obtained show that all compounds show activity against all bacteria and candida. The prepared compounds were characterized by FT-IR, 1HNMR and also studied the physical properties

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Published

2023-01-24

How to Cite

Abbas A. Mohammed, Hamid H. Mohammed, Mustafa T., & Zainab N. Mageed. (2023). Synthesis and biological activity of 2-(4,5-dihydro-1H-pyrazol-1-yl)-1,3-benzothiazole derivatives. Journal of Kufa for Chemical Sciences, 2(8), 109–126. Retrieved from https://journal.uokufa.edu.iq/index.php/jkcs/article/view/11086

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