Synthesis and biological activity of 2-(4,5-dihydro-1H-pyrazol-1-yl)-1,3-benzothiazole derivatives
Keywords:
Benzothiazole, Antibacterial activity, Antifungal activity, PyrazoleAbstract
In this work include synthesis some of 2-(4,5-dihydro-1H-pyrazol-1-yl)-1,3-benzothiazole derivatives were synthesized from 2-hydrazino-1,3-benzothiazole with dicarbonyl compounds, compounds (8 and 9) synthesis with microwave assistance. The biological activity for some compounds (2-5) were studied against (gram +ve) bacteria, (gram –ve) bacteria; and antifungal activity against and the data obtained show that all compounds show activity against all bacteria and candida. The prepared compounds were characterized by FT-IR, 1HNMR and also studied the physical properties
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