Synthesis and Characterisation of New Hexahydropyrimidine Derivatives, and Study of Their Effect as Anti-parasite.

Authors

  • Meaad K. Al-Shuraify Department of chemistry/ College of Science/ University of Basrah/ Iraq.
  • Fatima S. Sabah Department of chemistry, College of science, Basrah University.
  • Hanoy K. Al-Amood Department of chemistry, College of science, Basrah University.Iraq

Keywords:

Pyrimidine derivatives, hexahydropyrimidine, echinococcosis granulosus

Abstract

New pyrimidine derivatives (hexahydropyrimidine), 4-(2,4-dichlorophenyl)-6-phenyl-1,3-hexahydropyrimidine-2-amine (NH), and 6-(3-aminophenyl)-4-(2,4-dichlorophenyl)-1,3-hexahydropyrimidine-2-amine (Nm-NH2) were synthesised and identified with FT-IR, Mass and H1-NMR spectra. The new hexahydropyrimidine (NH, Nm-NH2)  applied to the parasite echinococcosis granulosus gave a different result. The prepared compounds' inhibition ratio was NH (78.9%) and Nm-NH2 (66.6%).  

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Published

2023-01-24

Issue

Vol. 2 No. 8 (2022): Journal Of Kufa For Chemical Sciences

Section

Peer-reviewed Articles

License

Copyright (c) 2022 Meaad K. Al-Shuraify, Fatima S. Sabah, Hanoy K. Al-Amood

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How to Cite

Meaad K. Al-Shuraify, Fatima S. Sabah, & Hanoy K. Al-Amood. (2023). Synthesis and Characterisation of New Hexahydropyrimidine Derivatives, and Study of Their Effect as Anti-parasite. Journal of Kufa for Chemical Sciences, 2(8), 13-26. https://journal.uokufa.edu.iq/index.php/jkcs/article/view/11092

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