Assessment of the correlation of lipasin levels with HOMA-IR score as an index of insulin resistance in type 2 diabetic Iraqi patients

Authors

  • Seenaa B. Mohammed Department of Chemistry and Biochemistry, College of Medicine, University of Babylon
  • Alaa. J. Mahrath Department of Chemistry and Biochemistry, College of Medicine, University of Babylon
  • Tariq. R. Abd College of medicine / Bablyon university

DOI:

https://doi.org/10.36329/jkcm/2024/v4.i1.15148

Keywords:

Diabetes, Insulin, Glucose

Abstract

Lipasin, a hormone found in the liver and adipose tissue, is involved in glucose homeostasis and lipid metabolism. Lipasin levels in plasma are controlled by food and rise after glucose consumption. Because plasma glucose and insulin levels both rise after eating, The study aims to elucidate if lipasin increases insulin sensitivity.

According to this study, the patient group's lipasin concentration increased significantly (p-value˂ 0.05) in comparison to the control group, and the area under the curve (AUC) for lipasin was 75.75 %.

The levels of insulin and glucose and also for the BMI were higher  (p-value˂ 0.05) in patient group in comparison to control group.

The results emphasize that Lipasin may play a crucial role in T2DM development.

 

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Published

2025-05-29

How to Cite

Seenaa B. Mohammed, Alaa. J. Mahrath, & Tariq. R. Abd. (2025). Assessment of the correlation of lipasin levels with HOMA-IR score as an index of insulin resistance in type 2 diabetic Iraqi patients. Journal of Kufa for Chemical Sciences, 4(1), 341-354. https://doi.org/10.36329/jkcm/2024/v4.i1.15148

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