Synthesis of a New Series of Ethyl Indolepropionates and Study of Their Biological Activity of Some Prepared Compounds

Authors

  • Haider Abd al ameer Abd al hadi
  • Naji Mousa Ali

Abstract

Ethyl indolepropionate derivatives were prepared by the decarboxylative ethanolysis of indole meldrum's acid derivatives in presence of copper powder, indole meldrum's acid derivatives were prepared earlier via Yonemitsu condensation. Their structures were identified on the basis of elemental analysis, IR, NMR and melting point. Also some of the prepared compounds have been tested for their antibacterial activity against pseudomonas aerogenosa (Gram positive) bacteria by using of agar well diffusion method. Finally we found that the compounds show different activity of inhibition of growth of the bacteria.

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Published

2012-04-15

How to Cite

Abd al ameer Abd al hadi, H., & Mousa Ali, N. (2012). Synthesis of a New Series of Ethyl Indolepropionates and Study of Their Biological Activity of Some Prepared Compounds. Journal of Kufa for Chemical Sciences, (4). Retrieved from https://journal.uokufa.edu.iq/index.php/jkcs/article/view/3427