Impact of Decreasing Blood Hemoglobin Concentration On Malondialdehyde, Reduced Glutathione Levels In Anemic Women During Pregnancy
Abstract
Abstract
The present study was conducted to verify the relationship between Hemoglobin (Hb) concentration (con), Reduced glutathione (GSH), and malondialdehyde (MDA) levels in 50 healthy woman and 100 pregnant anemic women .( anemic pregnant women) were divided into three groups, group 1 consisted of (9) patients with first trimester, group 2 contained 57 patients with second trimester, and group 3 comprised 34 patients with third trimester. the result exhibits a significant decrease (p<0.001) in blood hemoglobin concentration in pregnant anemic groups comparison to the control groups . In contrast, a significant increase (p<0.001) in MDA level in sera of women with pregnant, also a significant highly decrease was found in GSH level in sera of pregnant women in second and third trimester (p<0.001),While there was no significant differences in GSH level for women in first trimester as compared with control groups. Average total Hb con were observed in the first trimester was higher than Hb con in the second trimester , while , largest decrease was found in the third trimester, with a drop relative to the control serum total Hb con.
Key words: Reduced Glutathione, Malondialdehyde, Pregnancy, Oxidative Stress
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