PREPARATION, OXYGEN PERMEABILITY, OPTICAL TRANSPARENCY,WATER CONTENT,PROTEIN ADSORPTION AND EVALUATION OF BACTERIAL ADHESION PROPERTIES OF NEW SILICONE HYDROGEL THROUGH MODULATING SILICONE AND HYDROPHILIC MONOMER

Abstract

Silicone Hydrogel (SiHy) contact lenses are extremely fruitful in compare is onto preceding soft lenses; they were established to offer superior oxygen permeability. In the following paper, the hydrogel contact lenses based on silicone were made through the polymerization of 3- (methacryloyloxy) propyltris(trimethylsiloxy) silane (TRIS) with N,N dimethylacryl amide (DMA), Methyl methacrylate (MMA),and 2-hydroxyethyl methacrylate (HEMA). The features of silicone hydrogel lenses were studied depending on the approaches like equilibrium water component, oxygen permeability, optical transparency, protein adsorption, as well as cell toxicity.The outcomes revealed which the TRIS component in all makings rose the oxygen penetrability and decreased the equilibrium water component, while the DMA& HEMA participated the hydrophilicity of the silicon hydrogels and increases the equilibrium water content (EWC)%. The higher worth of oxygen penetrability was 102barrers, conforming to an equilibrium made of water component of 66%. generally, the silicone hydrogels in this work displayed decent oxygen permeability as well as optical transparency and anti protein adsorption. Hence forth, those polymers made of silicone hydrogel might be possible for manufacturing contact lens.