CHITOSAN SOURCES AND EXTRACTION: A REVIEW

Ruaa A.  Salman; Naser K.  Zedain

doi:10.30572/2018/KJE/160436

Authors

Ruaa A. Salman Biomedical Engineering Department, University of Technology-Iraq, Alsinaa Street 52, Baghdad, Iraq
Naser K. Zedain Production and Metallurgy Engineering Department, University of Technology-Iraq, Alsinaa Street 52, Baghdad, Iraq

DOI:

https://doi.org/10.30572/2018/KJE/160436

Keywords:

Extraction, Chitosan, Chitin, Polysaccharide, Biopolymer, Shrimp waste, Biotechnology

Abstract

Chitosan is a biopolymer that is obtained by deacetylating the chitin that is recovered from different sources, such as marine and animal. Also, the waste of agriculture and the seawater industry are considered good sources for extraction. This waste may be an environmental pollution source as a result of burning and dumping or a good source for producing important materials such as chitosan which is considered a biocompatible, biodegradable, biopolymer that has many industrial, biomedical, and agricultural applications. Chitosan material, extracted from chitin, has many attractive biomedical properties. This review focuses on the extraction methods of chitosan from different production sources, taking into account industrial considerations, and summarizes them, taking into account their environmental impacts and marketing potential. Also, this article reviews—based on existing publications—the classes of chemical methods and reaction parameters used in chitosan preparation and biological methods

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References

Abdel-Rahman, R. M., Hrdina, R., Abdel-Mohsen, A. M., Fouda, M. M., Soliman, A. Y., Mohamed, F. K., and Pinto, T. D. (2015) 'Chitin and Chitosan from Brazilian Atlantic Coast: Isolation, Characterization and Antibacterial Activity', International Journal of Biological Macromolecules, 80, 107-120.‏

Acosta, N., Jiménez, C., Borau, V., and Heras, A. (1993) 'Extraction and Characterization of Chitin from Crustaceans', Biomass and Bioenergy, 5(2), 145-153.‏

Ahmed, I. Z., Jaber, H.A., and Salih, Sh. M. (2021) 'Electrophoretic Deposition Used to Prepare and Analyze the Microstructure of Chitosan/Hydroxyapatite Nano-Composites', Engineering and Technology Journal, 39 ,11, 1693-1704.

Al Sagheer, F. A., Al-Sughayer, M. A., Muslim, S., and Elsabee, M. Z. (2009) 'Extraction and Characterization of Chitin and Chitosan from Marine Sources in Arabian Gulf', Carbohydrate polymers, 77(2), 410-419.‏

Ali, A., and Ahmed, S. (2018) 'A Review on Chitosan and its Nanocomposites in Drug Delivery', International journal of biological macromolecules, 109, 273-286.

Ali, M. A., Soud, S. A. , and Hameed, A. H. (2021) 'Chitosan Hydrogel for Removing of Heavy Metal Ions from Water: A Review', Engineering and Technology Journal, 39, 07, 1195-1205, available: DOI: https://doi.org/10.30684/etj.v39i7.2015.

Aranaz, I. , Mengibar, M. , Harris, R. , Panos, I. , Miralles, B. , Acosta, N. , Galed, G. , Heras, A. (2009) 'Functional characterization of chitin and chitosan', Curr. Chem. Biol., 3(2), 203–230.

Bello, VE., and Olafadehan, OA. (2021) 'Comparative Investigation of RSM and ANN for Multi-response Modeling and Optimization Studies of Derived Chitosan from Archachatina Marginata Shell', Alexandria Eng J, 1, 60(4), 3869–99.

Casadidio, C., Peregrina, D.V., Gigliobianco, M.R., Deng, S., Censi, R., Di Martino P(2019) 'Chitin and Chitosans: Characteristics, Eco-Friendly Processes, and Applications in Cosmetic Science', Mar Drugs, 2019, 21;17(6):369.

Chai, J., Hang, J., Zhang, C., Yang, J., Wang, S., Liu, S., and Fang, Y. (2020) ',Purification and Characterization of Chitin Deacetylase Active on Insoluble Chitin from Nitratireductor Aquimarinus MCDA3-3', International Journal of Biological Macromolecules, 152, 922-929.‏

Chen, X., Yang, H., Zhong, Z., and Yan, N. (2017) 'Base-Catalysed, One-step Mechanochemical Conversion of Chitin and Shrimp Shells Into Low Molecular Weight Chitosan', Green Chemistry, 19(12), 2783-2792.‏

Dai, L., Wang, Y. , Li, Z.X., Wang, X.W., Duan, C., Zhao, W., Xiong, C.Y., Nie, S.X., Xu, Y.J., and Ni, Y.H., (2020) 'A Multifunctional Self-Crosslinked Chitosan/Cationic Guar Gum Composite Hydrogel and Its Versatile Uses in Phosphate-Containing Water Treatment and Energy Storage', Carbohydr. Polym.,244, 116472.

Devi, R., and Dhamodharan, R. (2018) 'Pretreatment in Hot glycerol for Facile and Green Separation of Chitin from Prawn Shell Waste', ACS sustainable chemistry & engineering, 6(1), 846-853.‏

Dhillon, G. S., Kaur, S., Brar, S. K., and Verma, M. (2013) 'Green Synthesis Approach: Extraction of Chitosan from Fungus Mycelia', Critical reviews in biotechnology, 33(4), 379-403.‏

Duan, C., Meng, X., Meng, J.R., Khan, M.I.H., Dai, L., Khan, A., An X.Y., Zhang, J.H., Huq, T., Ni, Y.H. (2019) 'Chitosan as A preservative for Fruits and Vegetables: A Review on Chemistry and Antimicrobial Properties', J. Bioresour. Bioprod., 4(1), 11–21.

Fatehi, P., Kititerakun, R., Ni, Y.H., Xiao, H.N. (2010) 'Synergy of CMC and Modified Chitosan on Strength Properties of Cellulosic Fiber Network', Carbohydr. Polym., 80, 208–214 .

Fournier, P., Szczepanski C.R., Godeau R-P, Godeau G. (2020) 'Chitosan Extraction from Goliathus orientalis Moser, 1909: Characterization and Comparison with Commercially Available Chitosan', Biomimetics, 26, 5(2):15.

Ghormade, V. , Pathan, E.K. , Deshpande, M.V. (2017) 'Can Fungi Compete with Marine Sources for Chitosan Production', Int. J. Biol. Macromol, 104, 1415–1421.

Guibal, E. (2004) 'Interactions of Metal Ions with Chitosan-based Sorbents: A Review', Sep Purif Technol, 15; 38(1):43–74.

Gutiérrez, T. J. (2017) 'Chitosan Applications for the Food Industry Chitosan: Derivatives', Composites and Applications, 183-232.‏

Hemmami, H., Ben Amor, A., Zeghoud, S., Ahmed, S., Alnazza, A. A. (2024) 'Chitosan, Its Derivatives, Sources, Preparation Methods, and Applications: A Review', JOTCSA. 2024, 11(1):341-64.

Hosney, A., Ullah, S., and Barčauskaitė, K. (2022) 'A Review of the Chemical Extraction of Chitosan from Shrimp Wastes and Prediction of Factors Affecting Chitosan Yield by Using an Artificial Neural Network', Marine Drugs, 20(11), 675.

Huq, T., Khan, A., Brown, D., Dhayagude, N., He, Z., and Ni, Y. (2022) 'Review Production and Commercial Applications of Fungal Chitosan: A Review', Journal of Bioresources and Bioproducts, 7(2), 85-98.‏

Iber, B. T., Kasan, N. A., Torsabo, D., and Omuwa, J. W. (2022) 'A review of Various Sources of Chitin and Chitosan in Nature', Journal of Renewable Materials, 10(4), 1097.‏

Jayakumar, R., Nwe, N., Tokura, S., and Tamura, H. (2007) 'Sulfated Chitin and Chitosan as Novel Biomaterials', International Journal of Biological Macromolecules, 40(3), 175-181.

Jin, J., Song, M., and Hourston, D. J. (2004) 'Novel Chitosan-based Films Cross-linked by Genipin with Improved Physical Properties', Biomacromolecules, 5(1), 162-168.‏

Kaczmarek, MB., Struszczyk-Swita, K., Li, X., Szcz˛ esna-Antczak, M. and Daroch, M. (2019) 'Enzymatic Modifications of Chitin, Chitosan, and Chitooligosaccharides', Front. Bioeng. Biotechnol., 7, 243. doi: 10.3389/fbioe.2019.00243

Kadhim, I.A., Abdul Ameer, Z.J., and Alzubaidi, A.B. (2019) 'Synthesis and Characterization of Chitosan-Polyvinyl Alcohol Blend Modified by Genipin and Nanohydroxyapatite for Bone Tissue Engineering', Engineering and Technology Journal, 37(A), 11, 470-474.

Kawada, J., Yui, T., Okuyama, K., and Ogawa, K. (2001) 'Crystalline Behavior of Chitosan Organic Acid Salts', Biosci Biotechnol Biochem, 22, 65(11), 2542–7.

Khan, A., Wang, B., and Ni, Y. (2020) 'Chitosan-nanocellulose Composites for Regenerative Medicine Applications', Current Medicinal Chemistry, 27(28), 4584-4592.

Khan, M. I., An, X., Dai, L., Li, H., Khan, A., and Ni, Y. (2019) 'Chitosan-based Polymer Matrix for Pharmaceutical Excipients and Drug Delivery', Current Medicinal Chemistry, 26(14), 2502-2513.

Khayria, M., Abdel, G., Hifney, A.F., Fawzy, M.A., Gomaa, M. (2017) 'Technology Optimization of Chitosan Production from Aspergillus Niger Biomass and Its Functional Activities', Food Hydrocoll,63, 593–601.

Kiuchi, H., Kai, W., and Inoue, Y. (2008) 'Preparation and Characterization of Poly (Ethylene Glycol) Crosslinked Chitosan Films', Journal of Applied Polymer Science, 107(6), 3823-3830.‏

Kumari, S. , and Rath, P.K. (2014) 'Extraction and Characterization of Chitin and Chitosan from ( Labeo Rohit) Fish Scales', Procedia Mater. Sci., 6, 482–489.

Lesage, G., and Bussey, H. (2006) 'Cell wall Assembly in Saccharomyces Cerevisiae', Microbiology and Molecular Biology reviews, 70(2), 317-343.‏

Lv, S., Liu, J., Zhou, Q., Huang, L., and Sun, T. (2014) 'Synthesis of Modified Chitosan Superplasticizer by Amidation and Sulfonation and Its Application Performance and Working Mechanism', Industrial and Engineering Chemistry Research, 53(10), 3908-3916.‏

Mahmood, F. A. (2024) 'Exploring the Characteristics and Effects of Date Palm Waste on Some Properties of Concrete: A Review', Kufa Journal of Engineering Vol. 15, No. 1, P.P. 47-61

Mao, X.; Guo, N.; Sun, J.; Xue, C. (2017) 'Comprehensive Utilization of Shrimp Waste Based on Biotechnological Methods: A Review', J. Clean. Prod., 143, 814–823.

Margoutidis, G., Parsons, V. H., Bottaro, C. S., Yan, N., and Kerton, F. M. (2018) 'Mechanochemical Amorphization of α-chitin and Conversion Into Oligomers of N-acetyl-d-Glucosamine', ACS Sustainable Chemistry & Engineering, 6(2), 1662-1669.‏

Marwa, A.S., and Asmaa, H.D., (2023) 'Performance Evaluation of the Reverse Osmosis Pilot Plant: Using Sodium Chloride and Magnesium Chloride', Kufa Journal of Engineering, Vol. 14, No. 2, P.P.1-11

Merzendorfer, H. (2011) 'The Cellular Basis of Chitin Synthesis in Fungi and Insects: Common Principles and Differences', European journal of cell biology, 90(9), 759-769.‏

Mohsin, T. M. (2023) 'Corrosion Behavior and Bio-Wettability of Thermally Oxidized Titanium Alloy Surface for Biomedical Applications', Kufa Journal of Engineering,14(3), P.P. 69-78

Moss, S.M., Moss, D.R., Otoshi, C.A., and Arce, S.M. (2010) 'An Integrated Approach to Sustainable Shrimp Farming', Asian Fish Sci., 23, 591–605.

Namus R. M., Abass M. H., Alali M., Zedin N. K. (2024) 'Using green Corrosion Inhibitor to Reduce Maintenance Cost for Carbon Steel Saline Water Storage Systems in the Oil Industry', KOM – Corrosion and Material Protection Journal 68 43-50, 43 DOI: 10.2478/kom-2024-0005.

Nwe, N., Furuike, T., and Tamura, H. (2010) 'Production of Fungal Chitosan by Enzymatic Method and Applications in Plant Tissue Culture and Tissue Engineering: 11 years of our progress, present situation and future prospects', Biopolymers, 7(135), e162.‏

Olusola, E. O., Israel, O. S., Margaret, O. I., Philip O. G., and Samson O. A. (2021) 'Compositions and Thermo-Chemical Analysis of Bovine and Caprine Bones', Kufa Journal of Engineering Vol. 12, No. 3, P.P. 56-68.

Pareek, N., Vivekanand, V., Saroj, S., Sharma, A. K., and Singh, R. P. (2012) 'Purification and Characterization of Chitin Deacetylase from Penicillium Oxalicum SAEM-51', Carbohydrate polymers, 87(2), 1091-1097.‏

Pellis, A., Guebitz, G.M., Nyanhongo, G.S. (2022) 'Chitosan: Sources, Processing and Modification Techniques', Gels, 8, 393. https://doi.org/10.3390/ gels8070393

Revathi, M., Saravanan, R., and Shanmugam, A. (2012) 'Production and Characterization of Chitinase from Vibrio Species, A head Waste of Shrimp Metapenaeus Dobsonii (Miers, 1878) and Chitin of Sepiella Inermis Orbigny, 1848', Advances in Bioscience and Biotechnology, 3(04), 392-397.‏

Rhim, J. W., Hong, S. I., Park, H. M., and Ng, P. K. (2006) 'Preparation and Characterization of Chitosan-Based Nanocomposite Films with Antimicrobial Activity', Journal of Agricultural and Food Chemistry, 54(16), 5814-5822.‏

Rinaudo, M. (2006) 'Chitin and Chitosan: Properties and Applications', Progress in Polymer Science, 31(7), 603-632.‏

Riyan, Al.R., Tawfiq, Al. J., Nafisa N. Ch. (2021) 'Chitosan and its Broad Applications: A Brief Review', Journal of Clinical and Experimental Investigations , 12 (4). https://doi.org/10.29333/jcei/11268

Ruaa, A. Salman, and Naser, K. Zedin, (2021) 'Effect Multiple Addition (TiO2 and Fly Ash) on Wear Behavior and Hardness of 2024 Al Alloy', Materials Science Forum Submitted, Vol. 1039, pp 201-208.

Saeed, A., Fatehi, P., and Ni, Y. (2011) 'Chitosan as a Flocculant for Pre-hydrolysis Liquor of Kraft-Based Dissolving Pulp Production Process', Carbohydrate Polymers, 86(4), 1630-1636.‏

Salih, S. E., Jawad, K. O. (2015) 'Comparing Effect of Adding LDPE, PP, PMMA on the Mechanical Properties of Polystyrene (PS) ', Eng. And Tech.Journal, Vol. 33,Part (A), No.6,.

Salman, R. A., Ajeel, S. A., Zedin, N. K., (2020) 'Influence of Sulphate and Chlorides Acidic Media on Mechanical and Corrosion Behavior of Fly Ash Particulate Reinforced 2024 Al/TiO2 Composites', IOP Conf. Series: Materials Science and Engineering 671, 012153. doi:10.1088/1757-899X/671/1/012153

Sami A. A., Khalid A. S., and Naser K. Z. (2020) 'Extraction of High Purity Amorphous Silica from Rice Husk by Chemical Process', IOP Conf. Series: Materials Science and Engineering 881, 012096. doi:10.1088/1757-899X/881/1/012096.

Sami A. A., Khalid A. S., and Naser K. Z. (2021) 'Evaluation of Acid Leaching Process and Calcination Temperature on the Silica Extraction Efficiency from the Sustainable Sources', Journal of Physics: Conference Series 1773, 012014. doi:10.1088/1742-6596/1773/1/012014

Santos, V. P., Marques, N. S., Maia, P. C., Lima, M. A. B. D., Franco, L. D. O., and Campos-Takaki, G. M. D. (2020) 'Seafood waste as Attractive Source of Chitin and Chitosan Production and their Applications', International journal of molecular sciences, 21(12), 4290.

Saood, Sh.A. and Sulaiman, G. M. (2016) 'Synthesis of Biocompatible Polymer Blend for Drug Delivery in Biomedical Applications’, Eng. And Tech.Journal, 34 (B), 6.

Seenuvasan, M., Sarojini, G., and Dineshkumar, M. (2020) 'Recovery of Chitosan from Natural Biotic Waste', Current developments in biotechnology and bioengineering, pp. 115-133.‏

Shen, J., Fatehi, P., and Ni, Y. (2014) 'Biopolymers for Surface Engineering of Paper-based Products', Cellulose, 21, 3145-3160.

Shin, C.S., Kim, D.Y., Shin, W.S. (2019) 'Characterization of Chitosan Extracted from Mealworm Beetle (Tenebrio molitor, Zophobas morio) and Rhinoceros Beetle (Allomyrina dichotoma) and their Antibacterial Activities. Int J Biol Macromol,15, 125:72–7.

Simionato, JI., Paulino, AT., Garcia, JC., Nozaki, J. (2006) 'Adsorption of Aluminium from Wastewater by Chitin and Chitosan Produced from Silkworm Chrysalides', Polym Int, Nov 22;55(11):1243–8.

Song, Y., Kim, M., Moon, C., Seo, D., Han, YS., Jo, YH. (2018) 'Extraction of Chitin and Chitosan from Iarval Exuvium and Whole Body of Edible Mealworm, Tenebrio molitor', Entomol Res 23, 48(3):227–33.

Synowiecki, J., and Al-Khateeb, N. A. (2003) 'Production, Properties, and Some New Applications of Chitin and Its Derivatives', Food Sci Nutr, 43(2):145-71. doi: 10.1080/10408690390826473.

Teli, MD., and Sheikh, J. (2012) 'Extraction of Chitosan from Shrimp Shells Waste and Application in Antibacterial Finishing of Bamboo Rayon', Int J Biol Macromol,1, 50(5):1195–200.

Thornber, K., Verner-Jeffreys, D., Hinchliffe, S., Rahman, M.M., Bass, D., Tyler, C.R. (2019) 'Evaluating Antimicrobial Resistance in the Global Shrimp Industry', Rev. Aquac., 12, 966–986.

Valenti,W., and Kimpara, J.M. (2011) 'Measuring Aquaculture Sustainability', World Aquac., 42, 26–30.

Yan, X., Zhao, D., Zhang, Y., Guo, W., Wang, W., Zhao, K., and Wang, X. (2018) 'Identification and Characterization of Chitin Deacetylase2 from the American White Moth, Hyphantria Cunea (Drury) ', Gene, 670, 98-105.‏

Yang, H., Gözaydın, G., Nasaruddin, R. R., Har, J. R. G., Chen, X., Wang, X., and Yan, N. (2019). Toward the Shell Biorefinery: Processing Crustacean Shell Waste Using Hot Water and Carbonic Acid. ACS Sustainable Chemistry & Engineering, 7(5), 5532-5542.‏

Younes, I., and Rinaudo, M. (2015) 'Chitin and Chitosan Preparation from Marine Sources. Structure, Properties and Applications', Marine drugs, 13(3), 1133-1174.‏

Yu, H., Hou, J., Namin, R. B., Ni, Y., Liu, S., Yu, S., and Nie, S. (2021) 'Pre-cryocrushing of Natural Carbon Precursors to Prepare Nitrogen, Sulfur Co-doped Porous Microcellular Carbon as An Efficient ORR Catalyst', Carbon, 173, 800-808.‏

Zedin, N. K., Ajeel, S. A., and Sukkar, K. A., (2020) 'Nanosilicon Powder Extraction as A Sustainable Source (from Iraqi Rice Husks) by Hydrothermal Process', AIP Conf. Proc. 2213, 020155. https://doi.org/10.1063/5.0000147

Zedin, N. K., Salman, R. A., and Jaber, A. A., (2022) 'Extraction of Cellulose Nanoparticles via Modified Thermochemical Processes from Agricultural Wastes', IJASEIT Vol.12, No. 2, ISSN: 2088-5334.

Zhao, Y., Park, R. D., and Muzzarelli, R. A. (2010) 'Chitin Deacetylases: Properties and Applications. Marine drugs, 8(1), 24-46.‏