Applications of Mesenchymal Stem Cells in Treatments of Domestic Animals
DOI:
https://doi.org/10.36326/kjvs/2023/v14i211728Keywords:
Bone marrow stem cell, cell-based therapy, mesenchymal stem cells, paracrine effects, therapeutic application, veterinary medicineAbstract
Mesenchymal stem cells: they have received great attention in the field of regenerative medicine due to their ability to differentiate into different cell types and their ability to secrete a wide range of biologically active molecules that repair and regenerate tissues. Stem cells are usually isolated from bone marrow, adipose tissue, or other adult tissues and can be grown in culture media to generate large numbers of cells. Stem cells are widely used in veterinary medicine: for the treatment of bone diseases, diseases of the respiratory and digestive systems, immune diseases. The therapeutic effect of stem cells is due to the anti-inflammatory and immunomodulatory effects of the cells themselves and their excretory products. In general, the continuous investigation and development of Veterinary key therapies is essential to improve animal health and well-being, promote Translational Medicine, and thereby benefit human health. Mesenchymal stem cells have been studied as a potential treatment for various gastrointestinal diseases in cattle, including inflammatory bowel disease and Colitis. Stem cells can be used to replace damaged or diseased tissue by differentiating between specific cell types required for repair and regeneration. Stem cells can also secrete factors that promote tissue regeneration, which can enhance their therapeutic potential. Diverse alternatives provide an attractive option for the possibility of developing clinical applications of stem cells in veterinary medicine.
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Copyright (c) 2023 Murtadha Abbas, S.V. Nadezhdin1, Danil V. Makakov Maklakov, Ismael Raheem Al-Muhana
This work is licensed under a Creative Commons Attribution 4.0 International License.