Spectroscopic, Against bacteria and cancer of a new schiff base and its complex with Cu+2 and Co+2 derived from methyl 4-amino benzoate

Abstract

In this study, Schiff-base ligand was prepared (LS1) by condensation (methyl 4-amino benzoate) with aldehyde (ortho-vanillin). The prepared schiff-base was identified by FT-IR, UV-Visible, Mass ¹H, and ¹³C-NMR spectroscopy. The electronic spectra of these Azomethine ligand was investigated in terms of acid-base properties, and determination of ionization constants at various pH values (6-12). The complexes were characterized by infrared spectroscopy and measurements of the percentage of copper (II) and the percentage of cobalt (II) using flame atomic absorption spectroscopy, as well as measurements of magnetic susceptibility, molar conductivity, and thermogravimetric analysis. Through the diagnosis and measurements, the geometric shape of the complexes was proposed. Its effectiveness was studied against two types of bacteria and against lung cancer cells.