Estimation and study of some Elements and Hormones in Women with Recurrent Miscarriage

Abstract

 Introduction : Recurrent miscarriage is defined as the loss of pregnancy due to more than one successive pregnancy, one after the other, before the twentieth week of pregnancy. Miscarriage is considered one of the complications of pregnancy. The reasons for miscarriage are wide-ranging, and among these reasons that are the focus of this study are (hormonal disturbances, nutritional factors, pollution, and the environment).Methods: The case-control study included 50 sick women suffering from primary and recurrent miscarriage and 40 healthy women with no history of miscarriage in Basra Governorate. Some trace elements (iron, zinc, and magnesium) were measured from blood serum, and a colorimetric technique was used using a spectrophotometer to study the extent to which a decrease in these elements affects the success of pregnancy. The level of some hormones, including thyroid hormones (TSh, progesterone, and testosterone), were also measured using the fluorescent immunoassay technique.Results: In this study, there was a decrease in the levels of trace elements (Fe, Mg, Zn) that were measured for women with first and recurrent miscarriages compared to the control group. The results for aborted women who lived in the district areas were found to be lower than in the city center areas, and they obtained Statistically significant P values ​​= 0.000. As for hormones, progesterone levels were at low levels for the aborted women compared to the control group, while TSH and testosterone levels were high among the aborted women for both the city center and the district compared to the control groups. P values ​​were = 0.000.Conclusions: A deficiency in the elements iron, zinc and magnesium has a negative effect on the success of pregnancy, and it also has an effect on the hormones TSH, progesterone and testosterone, so the nutrients must be preserved to have a successful pregnancy and the birth of a healthy child.