Toxicity of CaO Nanoparticles effect on Haematology and Histopathology of male Rabbits
DOI:
https://doi.org/10.31257/2018/JKP/2021/130202Keywords:
Calcium oxide nanoparticles, Toxicity, Ld50Abstract
Calcium oxide (CaO) nanoparticle (NP) was synthesized by a simple chemical method. The CaONPs were characterized by X-ray diffraction (XRD), Scanning Electron Microscope (SEM) analysis, and UV-absorption spectral studies. The average crystallite size was found to be ≈36nm and the band gap energy of the CaO nanoparticle was 1.9 eV. Toxicity tests were performed on adult rabbits dosed with compound CaONPs for a period of (3 weeks). Areas of necrosis, hemorrhages, and degenerations were seen histopathologically in the kidney, and liver after 3 weeks of administration of CaONPs, the data of hematology obtained was statistically evaluated using Finney’s Probit Analysis and the Toxicity test performed revealed that the Ld50 value was 0.5ml/kg. This study found that an increase in the proportion of calcium oxide in the blood leads to damage to the organs, like the liver and kidneys that are responsible for filtering the blood.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Rana Ismaeel Khaleel , Asmaa Hadi Mohammed
This work is licensed under a Creative Commons Attribution 4.0 International License.
Journal of Kufa-Physics is licensed under the Creative Commons Attribution 4.0 International License, which allows users to copy, to create extracts, abstracts, and new works from the Article, to alter and revise the Article, and to make commercial use of the Article (including reuse and/or resale of the Article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made and the licensor is not represented as endorsing the use made of the work. The authors hold the copyright for their published work on the JKP website, while KJP is responsible for appreciating citation for their work, which is released under CC-BY-4.0 enabling the unrestricted use, distribution, and reproduction of an article in any medium, provided that the original work is properly cited.
