KERATOCONUS DETECTION USING DEEP LEARNING
DOI:
https://doi.org/10.30572/2018/KJE/160217Keywords:
Keratoconus case, Convolutional neural networks (CNNs), MATLAB, GoogleNetAbstract
The eye is considered as one of the most complicated organs of the human body, with various ailments that can impact it. Eye diseases are any condition that disrupts its function, leading to vision problems or blindness caused by genetics and aging to injuries, infections, and environmental factors. Keratoconus is a condition where the cornea becomes thinner and bulges out, causing vision and visual impairment, and must be detected early to prevent potential complications. This paper used real data taken from TOMEY TMS-5 to build a dataset for convolutional neural networks (CNNs) GoogleNet algorithms to classify either a Keratoconus or a normal case. The suggested models provided correct decision up to 85% accuracy which is a good result compared to other approaches using raw data to avoid limiting decision to some parameters. The built dataset contains a group of patients (females and males) whose ages ranged from 14-75 years.
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Alsharman, N. and Jawarneh, I. (2020) ‘GoogleNet CNN Neural Network towards Chest CT-Coronavirus Medical Image Classification’ Journal of Computer Science, 16 (5): 620-625. DOI: https://doi.org/10.3844/jcssp.2020.620.625
Al-Timemy, A.H., Alzubaidi, L., Mosa, Z.M., Abdelmotaal, H., Ghaeb, N.H., Lavric, A., Hazarbassanov, R.M., Takahashi, H., Gu, Y. and Yousefi, S. (2023) ‘A Deep Feature Fusion of Improved Suspected Keratoconus Detection with Deep Learning’, Diagnostics,13(10), 1689-1689. available: https://doi.org/10.3390/diagnostics13101689. DOI: https://doi.org/10.3390/diagnostics13101689
Bernabé, O., Acevedo, E., Acevedo, A., Carreño, R. and Gómez, S. (2021) ‘Classification of eye diseases in fundus images’, IEEE Access, 9, 101267-101276. DOI: https://doi.org/10.1109/ACCESS.2021.3094649
Chicco, D. and Jurman, G. (2020) ‘The advantages of the Matthews correlation coefficient (MCC) over F1 score and accuracy in binary classification evaluation’, BMC Genomics, 21(1), 1-13. available: https://www.doi.org/10.1186/S12864-019-6413-7. DOI: https://doi.org/10.1186/s12864-019-6413-7
Degadwala, S., Vyas, D., Dave, H.S., Patel, V. and Mehta, J.N. (2021) ‘Eye melanoma cancer detection and classification using CNN’ In Second International Conference on Image Processing and Capsule Networks: ICIPCN 2021 2. Springer International Publishing. 489-497. DOI: https://doi.org/10.1007/978-3-030-84760-9_42
Dipu, N.M., Shohan, S.A. and Salam, K.M.A. (2021) ‘Ocular disease detection using advanced neural network based classification algorithms’, Asian Journal for Convergence in Technology (AJCT) ISSN-2350-1146, 7(2), 91-99. DOI: https://doi.org/10.33130/AJCT.2021v07i02.019
Du, F. Zhao, L. Luo, H. Xing. Q, Wu, J. Zhu, Y. Xu, W. He, W. Wu, J. (2024) Recognition of eye diseases based on deep neural networks for transfer learning and improved D-S evidence theory. BMC Med Imaging. 2024 Jan 18;24(1):19. doi: 10.1186/s12880-023-01176-2. PMID: 38238662; PMCID: PMC10797809. DOI: https://doi.org/10.1186/s12880-023-01176-2
Erdin, M. and Patel, L. (2023) ‘Early detection of eye disease using CNN’, International Journal of Advanced Research in Science, Communication, and Technology, 11, 2683-2690. DOI: https://doi.org/10.22214/ijraset.2023.50737
Faizur, R. Jamal, A. Afendi, A. (2024) ‘Multiclass Classification and Identification of the External Eye Diseases using Deep CNN’, Indian Journal of Science and Technology, 17(12): 1107-1116. https://doi.org/10.17485/IJST/v17i12.21 DOI: https://doi.org/10.17485/IJST/v17i12.21
Farooqui, A. Bhaede, A. Ansari, I. and Siddiqui, F. (2022) ‘Detection of eye disease using CNN’, International Journal of Advanced Research in Science, Communication, and Technology, 2, 509-514. DOI: https://doi.org/10.48175/IJARSCT-2486
Feng, R., Xu, Z., Zheng, X., Hu, H., Jin, X., Chen, D.Z., Yao, K. and Wu, J (2021) ‘KerNet: a novel deep learning approach for keratoconus and sub-clinical keratoconus detection based on raw data of the Pentacam HR system’, IEEE Journal of Biomedical and Health Informatics, 25(10), 3898-3910. DOI: https://doi.org/10.1109/JBHI.2021.3079430
Guo, C., Yu, M. and Li, J. (2021) ‘Prediction of different eye diseases based on fundus photography via deep transfer learning’, Journal of Clinical Medicine, 10(23), 5481. DOI: https://doi.org/10.3390/jcm10235481
Hazem, A., Rossen, M. H., Ramin, S.M. Hossein, N. Suphi, T. Ali, H. Al-Timemy, Alexandru, L. Siamak, Y. (2024) ‘Keratoconus Detection-based on Dynamic Corneal Deformation Videos Using Deep Learning’, ophthalmology science, 4(2). DOI: https://doi.org/10.1016/j.xops.2023.100380
Hersh A. M., Shahab W. K., Amin S. M. (2022) ‘A comparative evaluation of deep learning methods in digital image classification’ Kufa Journal of Engineering, 13(4), 53-69. DOI: https://doi.org/10.30572/2018/KJE/1305
Krizhevsky, A., Sutskever, I. and Hinton, G.E. (2012) ‘ImageNet classification with deep convolutional neural networks’, Advances in Neural Information Processing Systems, 25, 1097-1105.
Kuo, B.I., Chang, W.Y., Liao, T.S., Liu, F.Y., Liu, H.Y., Chu, H.S., Chen, W.L., Hu, F.R., Yen, J.Y. and Wang, I.J. (2020) ‘Keratoconus screening based on deep learning approach of corneal topography’, Translational Vision Science and Technology, 9(2), 53-53. DOI: https://doi.org/10.1167/tvst.9.2.53
Lavric, A., Anchidin, L., Popa, V., Al-Timemy, A.H., Alyasseri, Z., Takahashi, H., Yousefi, S. and Hazarbassanov, R.M. (2021) ‘Keratoconus severity detection from elevation, topography and pachymetry raw data using a machine learning approach’, EEE Access, 9, 84344-84355. DOI: https://doi.org/10.1109/ACCESS.2021.3086021
LeCun, Y., Bengio, Y. and Hinton, G. (2015) ‘Deep learning’ nature, 521(7553), 436-444. DOI: https://doi.org/10.1038/nature14539
Lennart, M. H. Denna, S. L. Veronika, E. Tim, J. F. Anna, H. Susanna, F. K. Efstathios, V. Armin, W. Christian, M. ‘Keratoconus Progression Determined at the First Visit: A Deep Learning Approach with Fusion of Imaging and Numerical Clinical Data’ Wertheimer Translational Vision Science and Technology May 2024, 13(7). doi:https://doi.org/10.1167/tvst.13.5.7 DOI: https://doi.org/10.1167/tvst.13.5.7
Li, F., Chen, H., Liu, Z., Zhang, X.D., Jiang, M.S., Wu, Z.Z. and Zhou, K.Q. (2019) ‘Deep learning-based automated detection of retinal diseases using optical coherence tomography images’, Biomedical Optics Express, 10(12), 6204-6226. DOI: https://doi.org/10.1364/BOE.10.006204
Mahmoud, H.A.H. and Mengash, H.A. (2021) ‘Automated keratoconus detection by 3D corneal images reconstruction’, Sensors, 21(7), 2326. DOI: https://doi.org/10.3390/s21072326
Matsuzaka, Y. and Uesawa, Y. (2023) ‘Computational Models That Use a Quantitative Structure-Activity Relationship Approach Based on Deep Learning’ Processes, 11(4), 1296. DOI: https://doi.org/10.3390/pr11041296
Mohamed, E., Marwa A. M. (2024) ‘Deep learning-based classification of eye diseases using Convolutional Neural Network for OCT images’, Frontiers in Computer Science, 5, https://doi.org/10.3389/fcomp.2023.1252295. DOI: https://doi.org/10.3389/fcomp.2023.1252295
Santos, L. (2020) Artificial Intelligence, GitBook. [Online]. Available: https://leonardoaraujosantos.gitbook.io/artificial- intelligence/machine learning/deep learning/ GoogleNet.
Shoieb, D.A., Youssef, S.M. and Aly, W.M (2016) ‘Computer-aided model for skin diagnosis using deep learning’ Journal of Image and Graphics, 4(2),122-129. DOI: https://doi.org/10.18178/joig.4.2.122-129
Subramanian, P. and Ramesh, G. (2022) ‘Keratoconus classification with convolutional neural networks using segmentation and index quantification of eye topography images by particle swarm optimization’, BioMed Research International, 9. DOI: https://doi.org/10.1155/2022/8119685
Szegedy, C., Liu, W., Jia, Y., Sermanet, P., Reed, S., Anguelov, D., Erhan, D., Vanhoucke, V. and Rabinovich, A. (2015) ‘Going deeper with convolutions’, In Proceedings of the IEEE conference on computer vision and pattern recognition, 1-9. DOI: https://doi.org/10.1109/CVPR.2015.7298594
Tran, S., Mohammed, I.S., Tariq, Z. and Munir, W.M. (2023) ‘The Detection of Keratoconus using a Three-Dimensional Corneal Model Derived from Anterior Segment Optical Coherence Tomography’, International Ophthalmology, available: https://doi.org/10.21203/rs.3.rs-2934921/v1. [Accessed 10. April,2024]. DOI: https://doi.org/10.21203/rs.3.rs-2934921/v1
Tripathi, P., Akhter, Y., Khurshid, M., Lakra, A., Keshari, R., Vatsa, M. and Singh, R. (2021) ‘MTCD: Cataract detection via near infrared eye images’, Computer Vision and Image Understanding, 214, 103303. DOI: https://doi.org/10.1016/j.cviu.2021.103303
William, F. and Zhu, F. (2021) ‘CNN models for eye state classification using EEG with temporal ordering’, In Proceedings of the 12th ACM Conference on Bioinformatics, Computational Biology, and Health Informatics.1-8. DOI: https://doi.org/10.1145/3459930.3471160
World Health Organization. (2020). Blindness and visual impairment. Available at: https://www.who.int/news-room/fact-sheets/detail/blindness-and-visual-impairment. [accessed1.November, 2023].
Yan, Y., Jiang, W., Zhou, Y., Yu, Y., Huang, L., Wan, S., Zheng, H., Tian, M., Wu, H., Huang, L. and Wu, L. (2023) ‘Evaluation of a computer-aided diagnostic model for corneal diseases by analyzing in vivo confocal microscopy images’, Frontiers in Medicine,10, 1164188. available at https://doi.org/10.3389/fmed.2023.1164188. DOI: https://doi.org/10.3389/fmed.2023.1164188
Zaki, W. Daud, M. Saad, A. Hussain, A. and Mutalib, H. (2021) ‘Towards automated keratoconus screening approach using lateral segment photographed images’, In 2020 IEEE-EMBS Conference on Biomedical Engineering and Sciences (IECBES). IEEE. 466-471. DOI: https://doi.org/10.1109/IECBES48179.2021.9398781
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