Correlation between t-wave Inversion in Lead 3 Electrocardiography and Mitral Valve Prolapse in Patient with Atypical Chest Pain and/or Palpation

Abstract

Back ground: Mitral valve prolapse (MVP) is disease present in 2- 3% of the general population.
Mitral valve prolapse may be found with mitral regurgitation, bacterial endocarditis, congestive heart failure, and even sudden death. Mitral valve prolapse may be refer to as syndrome that present with symptoms palpitation or any other physical finding. The diagnosis of MVP can be confirmed by echocardiography
Objectives: We aimed from this study to test the possible use of electrocardiography as primary survey tool to diagnose patient with mitral valve prolapse.
Methodology: In this cross sectional study, we involve 75 patients with palpation and atypical chest pain. All these persons had been selected from those patients visit the internal medicine consult department and echocardiography unit in Al-Sadr medical city from January 2013 to January 2016. For all patient's data collected about age, sex, blood pressure, laboratory finding of lipid profile, electrocardiography and echocardiography.
Results: During period of this study which extends over 2 years, 75 patients of MVP enrolled in this screening research. Statistical analysis shows that sensitivity of electrocardiography as screening tool for diagnosis of MVP in a patient with atypical chest pain = 98.41, were its specificity = 90.9, positive predictive value = 98.41, negative predictive value = 90.9 so that as shown electrocardiography are highly specific and sensitive and this can use to diagnose MVP as it sensitive or exclude diagnosis of MVP as it specific.
Conclusion:
1. we found that T-wave inversion in lead 3 of ECG is unique change in ECG for mitral valve prolapse
2. we found that T-wave inversion in lead 3 of ECG highly reliable tool in make diagnosis of mitral valve prolapse as it sensitive test
3. we found this tool highly specific so can safely exclude diagnosis of mitral valve prolapse if test negative
Recommendation: We recommend use T-wave inversion in lead 3 of ECG as screening tool for mitral valve prolapse, as this change in ECG sensitive and specific.