Histological changes in the tonsils of patients infected by Epstein –barr virus
DOI:
https://doi.org/10.36320/ajb/v9.i2.7582Keywords:
Histological changes , Epstein –barr virusAbstract
This study was conducted on 50 subjects whom had visited the AL-Sadder Medical City and Al-Hakeem hospital in AL- Najaf governorate. The subjects of this study were chronic or recurrent tonsillitis patients, their age ranged from 4 to 33 years.. The biopsy of tonsils were fixed in 10% neutral buffered formalin and then processed in routine histopathological techniques.
The histopathological changes revealed infiltration of the inflammatory cells, multinucleated giant cell, germinal hyperplasia and large abnormal lymphocytes can be seen. Slight-moderate lymphocyte infiltration and/or diffuse lymphocyte infiltration leading to the defect in the surface epithelium of tonsils.
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References
Baltz , M.;Giroud,C.and Crockett,j.(2002). Identifying Stages of EBV Infection. American Clinical Lab. pp. 20-22.
Turk, S. M., Jiang, R., Chesnokova, L. S., & Hutt-Fletcher, L. M. 2006. Antibodies to gp350/220 enhance the ability of epstein-barr virus to infect epithelial cells. J Virol, 80 (19), 9628–9633Addition of a prominent epitope affects influenza a virus-specific CD8+ T cell immunodominance hierarchies when antigen is limiting. J. Immunol.; 177: 2917–2925.
Hutt-Fletcher, L. M. (2007). EBV entry. J Virol; 81(15): 7825-32.
Bancroft, J. D. & Stevens, A. (1999). Theory and Practice of Histological Techniques. Fourth edition. New York: Churchill Livingstone
Schooley, R.T.; Johannsen, E.C. and Kaye, K.M.(2001). Principles and Practice of Infection Diseases. 5th ed. In Mandell GL, Bennet JE, Dolin R ed. Epstein Barr Virus (Infectious Mononucleosis). Philadelphia: Churchill Livingstone,181-20
Balfour, Jr.; Henry, H.; Carol, M.D., Holman, J.;M.D.; Heather, E.; Amy, B.; Karger, M.D.and Arthur, J. (2005). Epstein-Barr Virus DNAemia after Solid Organ Transplantation and Correlation with Posttransplant Lymphoproliferative Disease. Antiviral Research and Epidemiology and the National Institutes of Health 2 P01 DK13083-40
Fafi-Kremer, S. (2005). Long-term shedding of infection EBV after infectious mononucleosis. J Infect Dism. 191(6): 985-9.
Pudney , V.A.; Leese , A.M.; Rickinson , A.B. and Hislop, A.D. (2005) . CD8 + immunodominance among Epstein-Barr virus lytic cycle antigens directly refl ects the effi ciency of antigen presentation in lytically infected cells. J. Exp. Med. 201 : 349 – 360 .
Windfuhr, K.; Hunt, I. M.; Kapur, N.; Robinson, J.; Bickley, H. and Flynn, S. (2005). Suicide in schizophrenia: findings from a national clinical survey. May; 12(3): 139-47.
Young, L. S. and Murray, P. G. (2003). Epstein-Barr virus and oncogenesis: from latentgenes to tumours. Oncogene, 22: 5108-5116.
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Copyright (c) 2017 Abbas Sabbar Dahkil Al-naely
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