An Association Between Celiac Disease Specific Autoantibody and Infertility in Male: Across Sectional Study
DOI:
https://doi.org/10.36320/ajb/v9.i2.7590Keywords:
infertility, celiac disease , IgA-tTG, oligozoospermiaAbstract
Background:The male infertility is considered a health problem ,which attributed to many factors such as genetic ,environmental , previous infections, bad lifestyle and others.these factors have been reported in previous studies.However, this study aimed to determine the effect of anti-tissue transglutaminase antibodies (IgA-tTG)as celiac disease product on the male infertility
Objective: This study was aimed to find out the incidence of celiac disease-specific antibodies, which is known as IgAanti-tissue transglutaminase antibodies (IgA-tTG) in the group of infertile male in Al-Najaf city by across sectional study.
Downloads
References
Baird D. T.; Benagiano G.; Cohen J. et al., “Physiopathological determinants of human infertility,” Human Reproduction Update, (2002) Vol 8(5): 435–47.
Dada R.; Kumar R.; Shamsi MB., et al. Genetic screening in couplesexperiencing recurrent assisted procreation failure. Indian JBiochem Biophys(2008) 45: 116-20.
Uehara S.; Hashiyada M.; Sato K.; Sato Y.; Fujimori K. and Okamura K. Preferential X-chromosome inactivation in women with idiopathic recurrent pregnancy loss.Fertility and Sterility.(2001) 76 908–14.
Hamada A.; Esteves S.C. and Agarwal A. Unexplained male infertility: potential causes and management.Human Andrology (2011) Vol(1)2-16.
Esch C.E.H.;Van Rijssen M.J.L.;Roos A.;Koning F.; Dekker F.W.; Mearin M.L.;Helmerhorst F.M. andSchweizer J.J. Screening for unrecognized coeliac disease in subfertile couples.Scandinavian Journal of Gastroenterology (2011): VOL(46) PP1423-28.
Filipponi D.; Feil R. Perturbation of genomic imprinting in oligozoospermia. Epigenetics. (2009);4:1, 27–30.
Wu W., Shen O., Qin Y., Niu X., Lu C., Xia Y., Song L., Wang S., Wang X.Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR).PLoS ONE (2011) Vol.5(11): e13884. doi:10.1371.
Azenabor A., Ekun A.O, and Akinloye O. Impact of Inflammation on Male Reproductive Trac. J Reprod Infertil.( 2015); 16(3): 123–29.
Fraczek M., Kurpisz M. Cytokines in the male reproductive tract and their role in infertility disorders. J Reprod Immunol. (2015) ;108:98-104.
Soares P.M., Borba E.F., Bonfa E., Hallak J., Corrêa A.L., Silva C.A.Gonad evaluation in male systemic lupus erythematosus.Arthritis Rheum. (2007);56(7):2352-61.
Marzari R., Sblattero D., Florian F., Tongiorgi E., Not T., Tommasini A.,Ventura A., Bradbury A. Molecular dissection of the tissue trans-glutaminase autoantibody response in celiac disease. J Immunol 2001;166:4170–76.
Caputo I., Barone M.V., Martucciello S., Lepretti M., Esposito C. Tissue transglutaminase in celiac disease: role of autoantibodies. Amino acid (2009) Vol 36, Issue 4, pp 693–99.
Wodzinska J.M. Transglutaminases as targets for pharmacological inhibition. Mini Rev Med Chem. 2005;5(3):279-92.
Elli L., Bergamini C.M., Bardella M.T., Schuppan D. Transglutaminases in inflammation and fibrosis of the gastrointestinal tract and the liver. Dig Liver Dis. (2009) 41(8):541-50.
Reif S. and Lerner A.Tissue transglutaminase--the key player in celiac disease: a review.Autoimmun Rev. (2004 )Jan;3(1):40-5.
Brezina P. R. , Yunus F. N. , Zhao Y . Effects of Pharmaceutical Medications on Male Fertility. J Reprod Infertil. (2012);13(1):3-11.
Kovács M. Szenes M, Horváth T. , Vajda G., Gasztonyi B., Bártfai G. Celiac disease as potential obstacle to childbearing. Open Journal of Obstetrics and Gynecolog, (2014) 4, 75-80
Hogen Esch C. E., Wolters V. M.,. Gerritsen S. A. M, . . Putter H., Blomberg M., Hoogstraten, I. M. W. v. Houwen R. H. J , Lely. N. v. d., and Mearin, M. L. Specific Celiac Disease Antibodies in Children on a Gluten-Free Diet. PEDIATRICS (2011); Vol 128( 3)547-52.
Magon N., Singh S., Saxena A.,2 and Sahay R.Growth hormone in male infertility Indian J Endocrinol Metab.( 2011) Sep; 15(3): 248–49.
Palmer N. O., Bakos H. W., Fullston T. and Lane M.Impact of obesity on male fertility, sperm function and molecular composition.Landes Bioscience(2012) 2:4, 253-63
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2017 Azhar Jasim Mohsin, Ali Ibrahim Rahim
This work is licensed under a Creative Commons Attribution 4.0 International License.
which allows users to copy, create extracts, abstracts, and new works from the Article, alter and revise the Article, and make commercial use of the Article (including reuse and/or resale of the Article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made and the licensor is not represented as endorsing the use made of the work.