Some bacteriological and clinical study of patients with vaginitis associated with intrauterine contraceptive device

Abstract

This study included (50) women suffering from vagintis associated with intrauterine contraceptive device  admitted to Al-Hilla Teaching Hospital during the period   from( June to August) 2008. Most patients presented with vaginitis and intrauterine contraceptive device. Age ranged between (15-50) years old.Vaginal swabs were taken from patients, all swabs were subjected to culture on available media and it was found that 20 samples revealed positive cultures, 18 pathogenic bacterial isolates most commonly  Escherichia coli (6)followed by  Staphylococcus  aureus and Klebsiella pneumoniae(3) ,Proteus mirabilis(2) ,and two isolates for each  Staphylococcs saprophyticus , Streptococcus agalagtiae and 2 yeast isolates where as 30 other swabs fail to give any growth. The effect of some  antibiotics on pathogenic bacterial isolates assessed by disk diffusion ests shows that most of isolates were sensitive to ciprofloxacin and less than to a mikacinRegarding the ability of  pathogenic bacteria to produce colonizing factors antigens, most of isolates produce first colonizing factors antigenCFA/I.S.aureus, P.mirabilis, Strep.agalagtiae ,S.saprophyticus, and three isolates of K.pnumoniae  produce second colonizing factor CFA/II. While all of K.pnumoniae and Strep. agalagtiae isolates produce third colonizing factor antigen CFA/III. Two isolates of E.coli produce CFA/III. S.aureus, P.mirabilis and S.saprophyticus not produce CFA/III.