Study the effect of Aqueous Extract of Allium porrum (leek) on Reproductive Hormone values in Female Rats

Authors

  • Wafaa H.AL-hashimi

DOI:

https://doi.org/10.36320/ajb/v7.i3.8069

Abstract

It shows significantly decrease(p<0.05)in FSH hormone of white female rats for both concentration 400,800 mg/kg and the concentration 800 mg/kg is more significant in reducing the level of FSH hormone comparing with control group, It also show significant decrease(p<0.05)in LH hormone of with female rats for both concentration 400,800 mg/kg and the concentration 800 mg/kg is more significant in reducing the level of LH hormone when compared with control group. While the prolactin hormone shows significant increase (p<0.05)  in white female rats for both concentration 400,800 mg/kg and the concentration 800 mg/kg is more significant in increasing the level of prolactin hormone. And the estradiol hormone shows significant increase (p<0.05)  in white female rats for both concentration 400,800 mg/kg and the concentration 800 mg/kg is more significant in increasing the level of estradiol hormone. In short comparing with control group. The aqueous of leek extract acts as anti-fertility in white female rats through its negative effects on the FSH, LH, prolactin and estradiol hormone.

Downloads

Download data is not yet available.

References

Daniel Z. and Maria H. , (2000). Domestication of plants in the Old World, third edition (Oxford: O. U. P.).page: 195.

. Seberg , Ole, (2007) . " Alliacea" . In Heywood , Vernon H .; Brummitt , Richard K . &Chulham , Alastair . flowering plant families of the world . Is. Bn 978-1-55407-206-4.

Chun O.K., Chung S.J., and Song W.O. (2007). Estimated dietary flavonoid intake and major food sources of U.S. adults. J Nutr. ;137(5):1244-1252. DOI: https://doi.org/10.1093/jn/137.5.1244

Calderon-Montaño J.M., Burgos-Moron E., Perez-Guerrero C. and Lopez-Lazaro M. (2011). "A review on the dietary flavonoid kaempferol.". Mini Rev Med Chem. 11 (4): 298–344. DOI: https://doi.org/10.2174/138955711795305335

Hou Y., Aboukhatwa M.A., Lei D.L., Manaye K., Khan I. and Luo Y. (2010) "Anti-depressant natural flavonols modulate BDNF and beta amyloid in neurons and hippocampus of double TgAD mice." Neuropharmacology. 58(6):911-920. DOI: https://doi.org/10.1016/j.neuropharm.2009.11.002

Movahedian A., Sadeghi H., Ghannadi A., Gharavi M. and Azarpajooh S.(2006). Hypolipidemic Activity of Allium porrum L. in Cholesterol-Fed Rabbits J. of Medical food., 9(1): 98-101. DOI: https://doi.org/10.1089/jmf.2006.9.98

Bridgette M.C., James W.A., Daniel E.F., Steven E., Christopher B.W., Stephen M.B., Stephen M.B., Tyler J.C., John A.M., Jawed A. and Matthew E.B.(2012) Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha. United States. The Journal of steroid biochemistry and molecular biology; 132(1-2):186-193.

Phillips K.M., Rasor A.S., Ruggio D.M., et al. (2008) Folate content of different edible portions of vegetables and fruits. Nutrition & Food Science 2008, 38(2):175-181. DOI: https://doi.org/10.1108/00346650810863055

Al- basri, Muhammad ibn al-Hasan (2010). Medicine of Imam Al-sadiq prepare and arrange by Aqeel Muhsin, Alaalma company publications Beirut – Lebanon .Pages 146.

Nasem, S.R. (1998). Antispermatogenic and androgenic activities of mormordicacharantia (Kerala) in albino rats. J.Ethrophsmacol; 61: 9-61. DOI: https://doi.org/10.1016/S0378-8741(98)00006-3

Amira, A.A. and Mohammed (2006). Evalution of the potential antifertility effect of fenugreek seeds in male and female rabbits research article; 73(3): 301 – 306. DOI: https://doi.org/10.1016/j.contraception.2005.08.020

AL- Shabani, S.A. (2011). Study the sexual and physiological variation that causes by extract of the Carrot plant seeds dacuscarota L. on the laboratory white rat, Master thesis, Faculty of science / University of kufa. Number of Pages 75.

Meethal S.V., Liu T., Chan H.W., Ginsburg E., Wilson A.C., Gray D.N., Bowen R.L., Vonderhaar B.K. and Atwood C.S. (August 2009). "Identification of a regulatory loop for the synthesis of neurosteroids: a steroidogenic acute regulatory protein-dependent mechanism involving hypothalamic-pituitary-gonadal axis receptors". J. Neurochem. 110 (3): 1014–1027. DOI: https://doi.org/10.1111/j.1471-4159.2009.06192.x

Porter M.B., Brumsted J.R. and Sites C.K. (2000).Effect of prolactin on follicle-stimulating hormone receptor binding and progesterone production in cultured porcine granulosa cells. FertilSteril. ;73(1):99-105 DOI: https://doi.org/10.1016/S0015-0282(99)00463-X

Mitsutoshi, S.D. and Serdar (2004). Estrogen up _ regulates cyclooxygenase_2via estrogen receptor in human uterine microvascular endothelial cell. Reproductive biology;18(5): 1351-1356. DOI: https://doi.org/10.1016/j.fertnstert.2003.09.076

Shrooq W.A. , Wafaa H.A. and Hawraa S.B.(2014). Histological histological study of aqueous extract of leek Allium porrum I. in femal reproductive system of laboratory white rats .Journal of Natural Science Research.ISSN: 2224-3186.

Collins-Burow B.M., Burow M.E., Duong B.N. and McLachlan J.A. (2000). Estrogenic and antiestrogenic activities of flavonoid phytochemicals through estrogen receptor binding-dependent and -independent mechanisms. Author information. Nutr Cancer : 38(2):229-244. 18. Collins-Burow B.M., Antoon J.W., Frigo D.E., Elliott S., Weldon C.B., Boue S.M., Beckman B.S., Curiel T.J., Alam J., McLachlan J.A., Burow M.E.( 2012). Antiestrogenic activity of flavonoid phytochemicals mediated via the c-Jun N-terminal protein kinase pathway. Cell-type specific regulation of estrogen receptor alpha. "antiestrogen" at Dorland's Medical DictionaryJ Steroid Biochem Mol Biol :132(1-2):186-193. DOI: https://doi.org/10.1016/j.jsbmb.2012.05.004

Riggins R.B., Bouton A.H., Liu M.C. and Clarke R. (2005). "Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer" . Vitam. Horm. 71: 201–237. DOI: https://doi.org/10.1016/S0083-6729(05)71007-4

Zinger M., McFarland M.C. and Ben-Jonathan N. (2003). "Prolactin expression and secretion by human breast glandular and adipose tissue explants". J. Clin. Endocrinol. Metab. 88 (2): 689–696. DOI: https://doi.org/10.1210/jc.2002-021255

Downloads

Published

2015-12-30

How to Cite

H.AL-hashimi, W. (2015). Study the effect of Aqueous Extract of Allium porrum (leek) on Reproductive Hormone values in Female Rats. Al-Kufa University Journal for Biology, 7(3), 9–14. https://doi.org/10.36320/ajb/v7.i3.8069