SEROLOGICAL STUDY OF HEPATITIS B VIRUS IN THE CHILDREN AT THE MIDDLE EUPHRATE AREA
DOI:
https://doi.org/10.36320/ajb/v12.i1.8144Keywords:
Hepatitis B, Thalassemia, ELIZA, ASTAbstract
This study was conducted to detect genotypes and the spread of infection with viral hepatitis B type among children of both sexes (from newborns until the age of 16 years) in four provinces of the middle Euphrates provinces (Najaf, Karbala, Babel, and Diwaniya), 422 samples were collected from seven specialized hospitals (one hospital in Najaf and two hospitals from each of the three remaining provinces). There were 76 samples from children with thalassemia and the other 346 samples were random samples from children.
The following technologies, ELIZA (HBsAb, HBsAg) and biochemical measurements of AST and ALT enzyme levels were applied. The percentage of cases of total viral hepatitis B that showed positive results for ELIZA HBsAb test were 8.767 % from total samples, and for ELIZA HBsAg tests, were 0.01 % from total samples.
It was found that 15 out of 43 patients show elevation of ALT enzyme or AST enzyme or both enzymes over the normal value. All thalassemic patients show elevation in both ALT enzyme and AST enzyme.
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Copyright (c) 2020 Roaa Mohammed Chessab, Karar Mohammed Abdul-Sada
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