Detection of Autoimmune Hepatitis among Chronic Cases of Hepatitis B virus in AL-Najaf province
DOI:
https://doi.org/10.36320/ajb/v8.i2.9265Keywords:
Autoimmune, Hepatitis, HBVAbstract
This study was amid to investigate the existence of HBV and the diagnosis of autoimmune hepatitis (AIH) in addition study (C3, C4) Levels among chronic hepatitis B patients. The current study was conducted on 360 patients suspected with hepatitis B virus infection, which have age ranging (11-72) year were collected from center health laboratory, AL-Hakeem hospital, and AL-Sadder medical city in AL-Najaf city, during the period from January (2013) to August (2013). Fifteen healthy individuals without any evidence of chronic inflammatory disease involved as control, age ranging (21-50) years. The results showed that only 76 were seropositive hepatitis B in ELISA technique , the age group (44-54) year revealed high significance(p<0.05) than other age groups. While 35 (46%) out of 76 seropositive with HBc Ab, the age group (55-65) year showed high significant (p<0.05) than other age groups, and male more infection than female. The result also revealed that the autoimmune hepatitis disease was 5 (6.5%) out of 76 patient infected with Type 1autoimmune hepatitis. Complement fractions C3, decreased in all patients compared to those of a healthy control, while the autoimmune hepatitis patient recorded high level was 142.2±8 mg/dI. In regard to C4 was revealed normal concentration in all patients compared with control groups while the autoimmune hepatitis patient recorded high level was 41.7±5.1 mg/dI and non-significant (P<0.0) in males than female in concentration of (C3 and C4).
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Copyright (c) 2017 Mohammed A. K. AL-Saadi, Huda Jameel AL-Khilkhali, Mohammed A. Muhsin
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