Association between Gallstone and Oral Contraceptive Pills

Abstract

Background: Recently, oral contraceptives have been the subject of concerns over the risk of gallbladder disease associated with their use.

Aim: The aim of this study was to determine the association between the use of oral contraceptive pills and gallstones.

Materials and Methods: The design of the study was descriptive analytic, involving 51 females consecutively recruited from the Teaching Hospital for Gastroenterology and Hepatology in Sulaimani Province/Kurdistan Region/Iraq from 3/7/2024 to 31/8/2024. The study tools included two parts. The data were collected through direct interviews, and the association between the use of oral contraceptives and gallstones was determined by chi-square. Statistical analysis was performed using the SPSS 24.0 software (IBM SPSS Statistics). The level of significance was set at p=0.01. Inferential statistics were used to analyze the data.

Results: The results show that 64.7% of the participants were older than 35 years, 33.3% were illiterate, 86.3% were housewives, and 64.7% lived in urban areas. Regarding BMI, 47.1% were overweight, and 52.9% had a family history of gallstones. There was a statistically significant association only between the level of education and the use of oral contraceptive pills. However, there was no statistically significant association between BMI, gallstones, and the use of oral contraceptive pills.

Conclusion: There was no statistically significant association between the use of oral contraceptive pills and gallstones.

Background: Recently, oral contraceptives have been the subject of concerns over the risk of gallbladder disease associated with their use.

Aim: The aim of this study was to determine the association between the use of oral contraceptive pills and gallstones.

Materials and Methods: The design of the study was descriptive analytic, involving 51 females consecutively recruited from the Teaching Hospital for Gastroenterology and Hepatology in Sulaimani Province/Kurdistan Region/Iraq from 3/7/2024 to 31/8/2024. The study tools included two parts. The data were collected through direct interviews, and the association between the use of oral contraceptives and gallstones was determined by chi-square. Statistical analysis was performed using the SPSS 24.0 software (IBM SPSS Statistics). The level of significance was set at p=0.01. Inferential statistics were used to analyze the data.

Results: The results show that 64.7% of the participants were older than 35 years, 33.3% were illiterate, 86.3% were housewives, and 64.7% lived in urban areas. Regarding BMI, 47.1% were overweight, and 52.9% had a family history of gallstones. There was a statistically significant association only between the level of education and the use of oral contraceptive pills. However, there was no statistically significant association between BMI, gallstones, and the use of oral contraceptive pills.

Conclusion: There was no statistically significant association between the use of oral contraceptive pills and gallstones.