Association between Serum Cholesterol Level and Giardia lamblia Infection among Children with Acute Diarrhea in Al-Najaf Governorate

Abstract

Background :Giardia is a disease that is transmitted directly to humans through contaminated water, ingestion parasite and through clothing and sexual contact. Increased risk of injury in children who suffer from malnutrition and delayed growth compared to healthy children.

The aim of the study: The purpose of this study was to detect the relationship between the severity of the infection of the parasite G.lamblia vegetative phase active and cholesterol in the blood and its impact on the patient.

Study Design: The study ways to case - control  of 1-12 / 2015 in the educational-Zahra hospital in the province of Najaf. Study of children up to age five who are suffering from diarrhea. This study examines the total cholesterol in the blood means that the 50 episodes of diarrhea passers Giardia trophozoite passers vegetative and compared with the proportion of cholesterol in the blood of 50 cases .Giardiasis is the most common waterborne disease in human. Infected children revealed malnutrition and growth retardation compare to health group and may lack the important caloric source and lipid malabsorption .

Methods :Study design: The case control study of 1-12 / 2015 in Zahra educational children's section of a hospital in the province of Najaf. A study of children up to age five who are suffering from diarrhea. This study examines the mean serum total cholesterol to 50 episodes of diarrhea passers Giardia trophozoite passers vegetative and compared with cholesterol in the blood of 50 cases of diarrhea in children infected with Giardia .. weight rate (9.85 to 18.2) kg and average height (75, 55 to 109.15 cm)

Results: There was a significant difference in mean serum cholesterol between cases and control groups (PË‚ 0.05) . The total cholesterol  serum level significantly declined by severity of giardiasis. (Table 2) . The total cholesterol  level inversely correlated with the severity of the disease . The serum level of cholesterol and gender of the patients showed no significant  relationship ( P˃ 0.05) .

Conclusions: the results suggest that there is a significance of G.lamblia on lipid levels and have ability to keep low serum cholesterol.

Recommendations

1. Promote scientific research students to pursue the study of deep research in the pathogenesis Giardia.

2. Engage with each branch of science or scientific institution with irrelevant.