Relationship Between Toxoplasmosis And Antiphospholipid Antibodies Igg, Igm In Aborted And Non Aborted Women

Abstract

Objectives: The study was designed to an estimate the prevalence of antiphospholipid IgG and IgM antibodies with toxoplasmosis patients among aborted and non-aborted women.

Methodology: A total number of 70 Iraqi patients aborted and non-aborted women were included in the present study. In addition, a total of 30 apparently healthy women and negative for antiphospholipid IgG and IgM antibodies were selected as a control group. The study was carried out during the period of October 2012 till January 2013. Blood samples and laboratory investigation was in Teaching Laboratory of the Medical city of Baghdad, using to detect antibodies type IgG and IgM for antiphospholipid and Toxoplasma gondii by utilize ELISA technique according to standard procedures describe by manufacturer.

Results: The results showed that the age stratum (21-30) years was found to be highly frequent in both studied
groups was significant (P<0.05). In addition, positive toxoplasmosis IgG antibodies testing in aborted women was higher than that observed in non - aborted women group, significant (P < 0.05). Present study illustrated that the total abortion cases was with positive in APL-IgM-Ab 12/58 (20.7%), whereas 46/58 (79.3%) was negative the statistical analysis were high significant. The results of our study demonstrate significant positive correlation between abortion toxoplasmosis IgG and IgM .

Conclusion: The present study demonstrates a strong association between infectious agent Toxoplasma gondii and
abortion in women with anti-phospholipids antibodies. Positive toxoplasmosis IgM and IgG antibodies testing in
abortion more than non-abortion. The frequency of anti-phospholipids antibodies IgM and IgG positive in abortion
more than non- abortion.

Recommendation: cannot be according to the antiphospholipid antibodies IgG and IgM in abortion cases. So that
further studies are needed to study the relationship between rubella virus and cytomegalovirus with anti-phospholipid antibodies.