Preparation and Characterization of complexes VO(IV) and Cu(II) with the new ligand (1,2-diphenylethane-1,2-diylidene-bis(hydrazine-2,1-iylidene))bis (methan-1-yl-1-ylidene)diphenol (DEDHIMD) and study biological activaty

Abstract

The new ligand of (1,2-diphenylethane-1,2-diylidene-bis(hydrazine-2,1-iylidene))bis (methan-1-yl-1-ylidene)diphenol (DEDHIMD)، has been prepared by reacting Salicyladehyde  with Benzil dihydrazone (prepared from benzil with hydrazine in ethanol)  in ethanol. This Ligand has been Identified by Using ¹HNMR، UV-Vis.& FTIR Spectra. We have also prepared chelate complex by reacting this ligand with metal ions VO(IV) and Cu(II).The preparation has been conducted after fixing the optimum conditions of concentration. U.V-Vis. spectra of the complexes solution of the above metal ions with the ligand (DEDHIMD) have been studied for a range of concentrations  which obey Lampert-Beers Law. The structure of complex are deduced according to mole ratio method which was obtained from the spectroscopic studies of the complex solution. The ratio of metal: ligand obtained is (1:1) to the complexes ions. The (UV -Vis) absorption spectrum of complex in ethanol solution showed chromic shift، as compared with that of free ligand. The infrared spectra of the chelating complex have been studied، they were also compared with the ligand spectrum، they showed obvious changes in the band positions، some of them has been disappeared while others are shifted، this may indicate that a coordination between the metal ions and our ligand takes place. The conductivity measurements of our complexes have not shown that ionic character. Depending on these results، in addition to the measurements of magnetic susceptibility of our complexes it seems of these complexes are paramagnetic. We can conclude that the proposed geometrical structures of the complexes of VO(IV) and Cu(II) ions are octahedral. The determination of the biological activity of complexes  were carried out on  Pseudomonas averuginose, Serratia fonticola and Staphylococcus aureus  bacteria.