The antibacterial & antibiofilm activity of Punica granatum peel aqueous extract against some oral pathogen

Abstract

This study was designed to evaluate the antibacterial & antibiofilm activity of Punica granatum peel aqueous  extract against  oral pathogens from patients suffering from gingivitis and dental carrier. These isolates were 58.8% gram positive (Lactobacillus  spp.  ,Streptococcus  spp. and  Staphylococcus aurus) and 41.2% gram  negative (Klebseilla pneumonia  and pseudomonas aeruginosa). The  susceptibility of  these  different  bacterial  species  toward  the  aqueous extract  of this plant was applied  by  using well diffusion agar method.  The results  were compared with each other and with selected antibiotic ciprofloxacin  as positive control. Results showed that aqueous  extract  of Punica granatum had antibacterial activity against all isolates, on which the diameter of inhibition zone at concentration 200 mg/ml of this extract was 24mm for Lactobacillus  spp and 23 mm for Staph aureus and P.aeruginosa, while the Streptococcus spp. was only 18 mm.