Isolation and Identification of Candida spp. from oral immunocompromised patients with study of virulence factors
Abstract
The present study was conducted to isolation and identification of Candida spp. Isolated from immunocompromised patients with (Diabetes, Cancer & Kidney transplant) by different identification methods including direct examination, laboratory culture, biochemical tests and molecular method using polymerase chain reaction (PCR) technique and determine the virulence factors phenotypic to Candida spp. and genetic polymorphism in Candida albicans in secreted aspartyl proteinase (SAP2) .
During the period from October 2013 to February 2014, a total of 140 oral swab were collected from immunocompromised patients with attending to the three center in AL-Sadder Medical City (Oncology center and kidney center and Center for Diabetes and Endocrinology).In AL-Najaf Governorate, the samples were collected as following: - 110 mouth swabs from patients suffering from leukemia, prostate, stomach and bowel cancer, also 10 mouth swabs from kidney transplant patients and 20 mouth swabs from diabetes.
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Copyright (c) 2014 Iehab Yehiea Jabber AL-Ali, Fatima Abdul Hussein Mejbel
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