Effect of the relationship between vitamin C and serum ferritin on fertility.
DOI:
https://doi.org/10.36320/ajb/v10.i1.8207Keywords:
vitamin C, serum ferritin , fertilityAbstract
Eighty Eight subfertile women and fourty fertile women (control group) enrolled in this study. The subfertile women subdivided into two subgroups according to the cause of subfertility: first group are women with polycystic ovary syndrome (PCOS) including 45 women. Second group are women with unexplained subfertility including 43 women. Their age range (16-40) yr. At day 3 and day 13 of menstrual cycle estimation of serum level serum ferritin and vitamin C. The results show significant increase in serum ferritin value in women with PCOS at day 3 and day 13 of menstrual cycle. Serum ferritin is lower in subfertile women with unexplaiened subfertility but this decrement is not significant. No significant changes in vitamin C level.
Downloads
References
Gurunath, S.; Pandian, Z.; Anderson, R. A.; Bhattacharya, S. (2011). "Defining infertility--a systematic review of prevalence studies". Human Reproduction Update 17 (5): 575.
Cooper, T.G.; Noonan, E. and Von Eckardstein, S. (2010): "World Health Organization reference values for human semen characteristics". Hum. Reprod. Update 16 (3): 231–45.
Edmonds, K. (2012): Dewhurst textbook of obstetrics and gynecology, eighth edition, pp: 487-592.
Gnoth, C.; Godehardt, E.; Frank-Herrmann, P.; Friol, K.; Tigges, J. Freundl, G. (2005): Definition and prevalence of subfertility and infertility. Hum Reprod. 20(5):1144-7.
Merekar Abhijit, N., Pattan, S. R. , Dighe, N. S., Kuchekar, B. S., (2009): FEMALE INFERTILITY –CAUSES AND THEIR DIAGNOSTIC TESTS: International Journal of Pharma Research and Development. Vol. (8).
Boomsma, C.M., Keay, S.D. and Macklon, N.S. (2007): Peri-implantation glucocorticoid administration for assisted reproductive technology cycles. Cochrane Database Syst Rev. (1): CD005996.
Kunz G, Leyendecker G. (2001): Uterine peristaltic activity during the menstrual cycle: characterization, regulation, function and dysfunction. Reprod Biomed; 4: 5–9.
Thiel, C. & Goss, D.J. (2009): Living with iron (and oxygen): questions and answers about iron homeostasis. Chem Rev,Vol. 109, No.10, pp.4568-79.
Wang, J. & Pantopoulos, K. (2011): Regulation of Cellular Iron Metabolism, Biochem J, Vol.434, pp: 365-81.
He, X.; Hahn, P.; Lacovelli, J.; Wong, R.; King, C.; Bhisitkul, R.. (2007): Iron Homeostasis and Toxicity in Retinal Degeneration. Prog Retin Eye Res, Vol.26, No.6, pp: 649-73.
Eschbach, J.W. (2005): Iron requirements in erythropoietin therapy. Best Pract Res Clin Haematol. (18): 347-61.
Chavarro, J. E.; Rich-Edwards, J.W.; Rosner B. A. and Willett. W. C. (2006): "Iron Intake and Risk of Ovulatory Infertility." Obstet Gynecol. 108.5 1145-52.
Westphal, L.M., Polan, M.L. and Trant, A.S. (2004): A nutritional supplement for improving fertility in women: a pilot study. Journal of Reproductive Medicine, 49: 289-93.
Montecinos, V.; Guzman, P.; and Munoz-montesinc, C. (2007): Vit C is essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells J. Biol. Chem., vol., 282(21): 15506-15.
Eteng, M.U.; Ibeekwe, H.A.; Uboh, F.U. (2006): Effect of Vitamin C on serum lipids and electrolyte profile of albino wistar rats. Nigerian Journal of Physiological Sciences, 21 (1-2): 15-9.
Padayatty, S.; Katz, A, Wang Y.; Eck, P.; Known, O. etal., (2003): Vitamin C as an antioxidant: evaluation of its rote in disease prevention. J. Am. Coll. Nutr., 22(1): 18-35.
Al-Katib, S. R. and Al-Kaabi M.M. (2013): Effects of vitamin “C” on the endometrial thickness and ovarian hormones of progesterone and estrogen in married and unmarried women. American Journal of Research Communication, 1(8): 24-31.
Gowenlock, A. H.; Mcmurry, J. R. and Melauchian, D. M. (1988): Practical clinical Biochemistry. 6th ed. Heinmann. Medical books, London. PP: 929 – 4.
Walker, S. W. (2010): Haematological values; Laboratory reference ranges. Ch. 28. In: Davidson's Principle and Practice of Medicine. Colledge, N. R.; Walker, B. R.; Ralston, S. H. PP: 1293-1298.
Briggs DA, Sharp DJ, Miller D, Gosden RG(1999): Transferrin in the developing ovarian follicle: evidence for de-novo expression by granulosa cells. Mol Hum Reprod;5: 1107–14
Sharifi, F., Mazloomi, S. and Mousavinasab, N. (2011): High Serum Ferritin Concentrations in Polycystic Ovary Syndrome Is Not Related to Insulin Resistance. IRANIAN JOURNAL OF DIABETES AND OBESITY, VOLUME 3, NUMBER 225.
Escobar-Morreale, H.F., Luque-Ramírez, M., Álvarez-Blasco, F., Botella-Carretero, J.I., Sancho, J. and San Millán, J.L. (2005): Body iron stores are increased in overweight and obese women with polycystic ovary syndrome. Diabetes Care ; 28(8):2042-4.
Martínez-García, M.A., Luque-Ramírez, M., San-Millán, J.L. and Escobar-Morreale, H.F. (2009): Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism. Diabetes Care.32 (8):1525-30.
Sathiyanarayanan, S., Shyam Sundar, J., Madhankumar, E.K, Praneetha, A., Kalaiselvi, S., Gopinath, P.M., Dakshayani, D., Krithika Devi, J, Sankar, C. and Ramesh, U. (2014): A study on significant biochemical changes in the serum of infertile women Volume-2 Number 2 pp.96-115.
Calls, J. C.; Phiri, K. S. and Faragher, E. B. (2008): "Sever anemia in Malawian children." N. Engl. J. Med. 358(9): 888-99.
Proteggente, A. R., Rehman, A.; Halliwell, B. And Rice, C. A., (2000): Potential problems of ascorbic acid and iron supplementation: prooxidant effect in vivo? Biochem. Biophys. Res. Commun., 277: 535-40.
Mathur, R. and Sharma, (1995): Correction of anemia and iron deficiency in vegetarians by administration of ascorbic acid. Indian J. Physiol. Pharmacol., 39(4): 403-6.
Hethir Rodriguez, B.S., M.H., and C.M.T, (2003): Vitamin C and infertility. Fertility and Sterility 80: (459–61).
.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2018 Sami R. Al- Katib, Maisem MH. Al-Kaabi, Wasen G. Al-Safi, Aseel Jassim Al-Bderi
This work is licensed under a Creative Commons Attribution 4.0 International License.
which allows users to copy, create extracts, abstracts, and new works from the Article, alter and revise the Article, and make commercial use of the Article (including reuse and/or resale of the Article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made and the licensor is not represented as endorsing the use made of the work.
